FAM98B Antibody (B-1): sc-398375

FAM98B Antibody (B-1) is a mouse monoclonal IgM antibody that detects FAM98B of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-FAM98B antibody (B-1) is available as the non-conjugated form. FAM98B plays a significant role in cellular processes, including cell proliferation and differentiation, which are crucial for normal development and tissue homeostasis. Understanding FAM98B function is particularly important as FAM98B may be involved in various pathophysiological conditions, including neurodevelopmental disorders linked to chromosome 15 abnormalities. FAM98B is located in a genomic region associated with several syndromes, such as Angelman and Prader-Willi syndromes, highlighting potential relevance in genetic research and therapeutic development. Through interactions with other proteins involved in critical cellular pathways, FAM98B may serve as a valuable biomarker for studying these complex diseases.

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FAM98B Antibody (B-1) References:

1. Analysis of the DNA sequence and duplication history of human chromosome 15.  |  Zody, MC., et al. 2006. Nature. 440: 671-5. PMID: 16572171
2. Effective gene therapy in an authentic model of Tay-Sachs-related diseases.  |  Cachón-González, MB., et al. 2006. Proc Natl Acad Sci U S A. 103: 10373-10378. PMID: 16801539
3. Pyrimethamine as a potential pharmacological chaperone for late-onset forms of GM2 gangliosidosis.  |  Maegawa, GH., et al. 2007. J Biol Chem. 282: 9150-61. PMID: 17237499
4. Molecular epigenetics of Angelman syndrome.  |  Lalande, M. and Calciano, MA. 2007. Cell Mol Life Sci. 64: 947-60. PMID: 17347796
5. [The Prader-Willi syndrome].  |  Diene, G., et al. 2007. Ann Endocrinol (Paris). 68: 129-37. PMID: 17499572
6. Detailed analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromes.  |  Makoff, AJ. and Flomen, RH. 2007. Genome Biol. 8: R114. PMID: 17573966
7. Fibrillin-rich microfibrils: Structural determinants of morphogenetic and homeostatic events.  |  Ramirez, F. and Dietz, HC. 2007. J Cell Physiol. 213: 326-30. PMID: 17708531
8. Extracellular control of TGFbeta signalling in vascular development and disease.  |  ten Dijke, P. and Arthur, HM. 2007. Nat Rev Mol Cell Biol. 8: 857-69. PMID: 17895899

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FAM98B Antibody (B-1) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-FAM98B Antibody (B-1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FAM98B Antibody (B-1) Specifications

Alternate Product Name: FAM98B

Product Clone Name: B-1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 65-86

Epitope Target: FAM98B

Epitope Species: human

Product Reactivity/Detection: FAM98B

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for FAM98B Antibody (B-1): P: Blocking Peptide