FAM96B Antibody (F-1): sc-376801
- FAM96B Antibody (F-1) is a mouse monoclonal IgG2b κ FAM96B antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 137-163 at the C-terminus of FAM96B of human origin
- FAM96B Antibody (F-1) is recommended for detection of FAM96B of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- Anti-FAM96B Antibody (F-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for FAM96B Antibody (F-1) for WB and IHC(P) applications. This reagent is now offered in a bundle with FAM96B Antibody (F-1) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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FAM96B Antibody (F-1) is a mouse monoclonal IgG2b kappa light chain antibody that detects FAM96B protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-FAM96B antibody (F-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FAM96B plays a crucial role in cellular stress responses and is involved in the regulation of protein homeostasis, which is vital for maintaining cellular function and preventing diseases related to protein misfolding. Located in the cytoplasm, FAM96B interacts with chaperone proteins to facilitate proper folding of newly synthesized proteins and assist in refolding of misfolded proteins, thereby contributing to cellular resilience against stressors such as heat shock and oxidative stress. Dysregulation of FAM96B has been implicated in various pathologies, including neurodegenerative diseases, where impaired protein folding can lead to accumulation of toxic aggregates. The gene encoding FAM96B is situated on chromosome 16, a region associated with several genetic disorders, highlighting the importance of FAM96B in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
FAM96B Antibody (F-1) References:
- Homozygosity mapping of giant axonal neuropathy gene to chromosome 16q24.1. | Ben Hamida, C., et al. 1997. Neurogenetics. 1: 129-33. PMID: 10732815
- Novel quantitative trait loci controlling development of experimental autoimmune encephalomyelitis and proportion of lymphocyte subpopulations. | Karlsson, J., et al. 2003. J Immunol. 170: 1019-26. PMID: 12517969
- Meta-analysis of genome-wide linkage studies of systemic lupus erythematosus. | Forabosco, P., et al. 2006. Genes Immun. 7: 609-14. PMID: 16971955
- Giant axonal neuropathy. | Yang, Y., et al. 2007. Cell Mol Life Sci. 64: 601-9. PMID: 17256086
- Genotype-phenotype analysis in patients with giant axonal neuropathy (GAN). | Koop, O., et al. 2007. Neuromuscul Disord. 17: 624-30. PMID: 17587580
- The Nodosome: Nod1 and Nod2 control bacterial infections and inflammation. | Tattoli, I., et al. 2007. Semin Immunopathol. 29: 289-301. PMID: 17690884
- Identification, evolution, and association study of a novel promoter and first exon of the human NOD2 (CARD15) gene. | King, K., et al. 2007. Genomics. 90: 493-501. PMID: 17719742
- High frequency of mosaic CREBBP deletions in Rubinstein-Taybi syndrome patients and mapping of somatic and germ-line breakpoints. | Gervasini, C., et al. 2007. Genomics. 90: 567-73. PMID: 17855048
- Nod-like receptors in innate immunity and inflammatory diseases. | Carneiro, LA., et al. 2007. Ann Med. 39: 581-93. PMID: 18038361
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FAM96B Antibody (F-1) | sc-376801 | 200 µg/ml | $316.00 | |||
FAM96B Antibody (F-1): m-IgGκ BP-HRP Bundle | sc-523099 | 200 µg Ab, 40 µg BP | $354.00 | |||
FAM96B Antibody (F-1) AC | sc-376801 AC | 500 µg/ml, 25% agarose | $416.00 | |||
FAM96B Antibody (F-1) HRP | sc-376801 HRP | 200 µg/ml | $316.00 | |||
FAM96B Antibody (F-1) FITC | sc-376801 FITC | 200 µg/ml | $330.00 | |||
FAM96B Antibody (F-1) PE | sc-376801 PE | 200 µg/ml | $343.00 | |||
FAM96B Antibody (F-1) Alexa Fluor® 488 | sc-376801 AF488 | 200 µg/ml | $357.00 | |||
FAM96B Antibody (F-1) Alexa Fluor® 546 | sc-376801 AF546 | 200 µg/ml | $357.00 | |||
FAM96B Antibody (F-1) Alexa Fluor® 594 | sc-376801 AF594 | 200 µg/ml | $357.00 | |||
FAM96B Antibody (F-1) Alexa Fluor® 647 | sc-376801 AF647 | 200 µg/ml | $357.00 | |||
FAM96B Antibody (F-1) Alexa Fluor® 680 | sc-376801 AF680 | 200 µg/ml | $357.00 | |||
FAM96B Antibody (F-1) Alexa Fluor® 790 | sc-376801 AF790 | 200 µg/ml | $357.00 | |||
FAM96B (F-1) Neutralizing Peptide | sc-376801 P | 100 µg/0.5 ml | $68.00 |