FAM53C Antibody (F-4): sc-514210

FAM53C Antibody (F-4) is a mouse monoclonal IgM antibody that detects FAM53C protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-FAM53C antibody (F-4) is available as the non-conjugated form. FAM53C protein plays a crucial role in cellular processes, particularly in gene expression regulation and cellular signaling pathways, which are vital for maintaining normal cellular function and responding to environmental stimuli. FAM53C (F-4) antibody targets a nuclear protein involved in modulating transcriptional activity, influencing cell growth and differentiation. Understanding FAM53C function and location is important, as dysregulation has been implicated in various diseases, including cancer and genetic disorders. FAM53C gene product has been provisionally designated FAM53C pending further characterization, and association with chromosome 5 highlights potential relevance in genetic conditions such as Cockayne syndrome and familial adenomatous polyposis.

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FAM53C Antibody (F-4) References:

1. Duodenal adenomatosis in familial adenomatous polyposis coli. A review of the literature and results from the Heidelberg Polyposis Register.  |  Kadmon, M., et al. 2001. Int J Colorectal Dis. 16: 63-75. PMID: 11355321
2. The gene for Treacher Collins syndrome maps to the long arm of chromosome 5.  |  Dixon, MJ., et al. 1991. Am J Hum Genet. 49: 17-22. PMID: 1676560
3. Cockayne syndrome exhibits dysregulation of p21 and other gene products that may be independent of transcription-coupled repair.  |  Cleaver, JE., et al. 2007. Neuroscience. 145: 1300-8. PMID: 17055654
4. A new genomic mechanism leading to cri-du-chat syndrome.  |  South, ST., et al. 2006. Am J Med Genet A. 140: 2714-20. PMID: 17103439
5. Redefining monosomy 5 by molecular cytogenetics in 23 patients with MDS/AML.  |  Herry, A., et al. 2007. Eur J Haematol. 78: 457-67. PMID: 17391336
6. Somatic APC mosaicism: a frequent cause of familial adenomatous polyposis (FAP).  |  Aretz, S., et al. 2007. Hum Mutat. 28: 985-92. PMID: 17486639
7. Telomerase reverse transcriptase haploinsufficiency and telomere length in individuals with 5p- syndrome.  |  Du, HY., et al. 2007. Aging Cell. 6: 689-97. PMID: 17875000
8. Molecular mechanisms of skin aging: state of the art.  |  Makrantonaki, E. and Zouboulis, CC. 2007. Ann N Y Acad Sci. 1119: 40-50. PMID: 18056953
9. A physical map of 15 loci on human chromosome 5q23-q33 by two-color fluorescence in situ hybridization.  |  Saltman, DL., et al. 1993. Genomics. 16: 726-32. PMID: 8325647

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FAM53C Antibody (F-4) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-FAM53C Antibody (F-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FAM53C Antibody (F-4) Specifications

Alternate Product Name: FAM53C

Product Clone Name: F-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 22-41

Epitope Target: FAM53C

Epitope Species: human

Product Reactivity/Detection: FAM53C

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for FAM53C Antibody (F-4): P: Blocking Peptide