EXOSC8 Antibody (2336C2b): sc-81561
- EXOSC8 Antibody (2336C2b) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to an internal region of EXOSC8 of human origin
- recommended for detection of EXOSC8 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for EXOSC8 Antibody (2336C2b). This work is in progress.
EXOSC8 Antibody (2336C2b) is a mouse monoclonal IgG1 antibody that detects EXOSC8 in human samples through western blotting (WB) and immunoprecipitation (IP) applications. EXOSC8, also known as p9, CIP3, EAP2, OIP2, and RRP43, is a crucial component of the exosome complex, which plays a vital role in the degradation of unstable mRNAs, particularly those containing AU-rich elements in their untranslated 3′ regions. EXOSC8 is primarily located in the nucleolus, where EXOSC8 contributes to the processing of 7S pre-RNA, a critical step in ribosomal RNA maturation. The localization of EXOSC8 within the nucleolus underscores EXOSC8′s involvement in ribonucleoprotein assembly and RNA processing, essential for maintaining cellular homeostasis and regulating gene expression. Furthermore, EXOSC8 is one of the six RNase-PH domain subunits that form a PNPase-like ring structure within the exosome, facilitating exoribonuclease activity. The ability of EXOSC8 to interact with itself and other proteins enhances functional versatility, making EXOSC8 a key player in various cellular processes. With specific reactivity and robust performance in applications, anti-EXOSC8 antibody (2336C2b) is an invaluable tool for researchers studying RNA metabolism and related pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EXOSC8 Antibody (2336C2b) | sc-81561 | 100 µg/ml | $339.00 |