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Exo70 Antibody (ZZ-7) is a mouse monoclonal IgG2a antibody that detects Exo70 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Exo70, also known as EXOC7, is a 735 amino acid peripheral membrane protein that plays a pivotal role in the exocyst complex, a multi-protein assembly essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Exo70 is primarily localized in the cytoplasm and at the cell membrane, where anti-Exo70 antibody (ZZ-7) can detect its involvement in docking processes crucial for membrane trafficking, hormone secretion, and cell-cell communication. Notably, Exo70 participates in insulin-induced protein docking, highlighting its importance in metabolic regulation and cellular signaling. Four isoforms of Exo70, resulting from alternative splicing, add complexity to its functional roles, allowing for diverse regulatory mechanisms in different cellular contexts. With critical involvement in exocytosis and membrane dynamics, Exo70 maintains cellular homeostasis and facilitates communication between cells, making Exo70 (ZZ-7) monoclonal antibody an invaluable research tool for studying these fundamental biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Exo70 Antibody (ZZ-7) | sc-100733 | 100 µg/ml | $339.00 |