EVA1B Antibody (H-6): sc-390824
- EVA1B Antibody (H-6) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 122-150 near the C-terminus of EVA1B of human origin
- recommended for detection of EVA1B of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and bovine
- m-IgG3 BP-HRP is the preferred secondary detection reagent for EVA1B Antibody (H-6) for WB applications. This reagent is now offered in a bundle with EVA1B Antibody (H-6) (see ordering information below).
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EVA1B Antibody (H-6) is a mouse monoclonal IgG3 antibody that detects EVA1B in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). EVA1B, also known as FAM176B or C1orf78, is a 165 amino acid single-pass membrane protein that plays a crucial role in cellular processes, particularly in the regulation of apoptosis and cell proliferation. EVA1B (H-6) antibody helps researchers study a protein vital for modulating cell death pathways, which can have significant implications in cancer biology and therapeutic interventions. Understanding EVA1B′s role in these processes is essential, as dysregulation of apoptosis is a hallmark of many cancers, and targeting this pathway could lead to novel treatment strategies. Additionally, EVA1B is post-translationally phosphorylated, which may influence activity and interactions with other proteins, further underscoring importance in cellular signaling networks. The gene encoding EVA1B is located on human chromosome 1, a region known for housing numerous disease-associated genes, making EVA1B a critical area of study in genetics and disease research.
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EVA1B Antibody (H-6) References:
- Identification of DNA-Methylated CpG Islands Associated With Gene Silencing in the Adult Body Tissues of the Ogye Chicken Using RNA-Seq and Reduced Representation Bisulfite Sequencing. | Lim, WJ., et al. 2019. Front Genet. 10: 346. PMID: 31040866
- Molecular Characteristics, Oncogenic Roles, and Relevant Immune and Pharmacogenomic Features of EVA1B in Colorectal Cancer. | Ma, B., et al. 2022. Front Immunol. 13: 809837. PMID: 35250982
- Construction and Validation of a Prognostic Model Based on mRNAsi-Related Genes in Breast Cancer. | Zhao, X. and Lin, J. 2022. Comput Math Methods Med. 2022: 6532591. PMID: 36267313
- Identification of a basement membrane-related gene signature for predicting prognosis and estimating the tumor immune microenvironment in breast cancer. | Cai, J., et al. 2022. Front Endocrinol (Lausanne). 13: 1065530. PMID: 36531485
- EVA1B facilitates esophageal squamous carcinoma progression and recruitment of immunosuppressive myeloid-derived suppressor cells in the tumor microenvironment. | Xia, T., et al. 2024. Pharmacol Res. 210: 107521. PMID: 39603573
- Targeting EVA1B in breast cancer: New avenues for precision oncology. | Hsiao, JH., et al. 2025. Pharmacol Res. 214: 107684. PMID: 40049427
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EVA1B Antibody (H-6) | sc-390824 | 200 µg/ml | $322.00 | |||
EVA1B Antibody (H-6): m-IgG3 BP-HRP Bundle | sc-550483 | 200 µg Ab; 40 µg BP | $361.00 | |||
EVA1B (H-6) Neutralizing Peptide | sc-390824 P | 100 µg/0.5 ml | $69.00 |