Ethanolamine kinase Antibody (3F11): sc-517100
- Ethanolamine kinase Antibody (3F11) is a mouse monoclonal IgG1 κ Ethanolamine kinase antibody provided at 100 µg/ml
- raised against amino acids 133-228 representing partial length Ethanolamine kinase of human origin
- recommended for detection of Ethanolamine kinase of human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Ethanolamine kinase Antibody (3F11). This work is in progress.
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Ethanolamine kinase Antibody (3F11) is a mouse monoclonal IgG1 kappa light chain antibody that detects Ethanolamine kinase protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Ethanolamine kinase antibody (3F11) is available as the non-conjugated format. Ethanolamine kinase (ETNK1) is a 452 amino acid protein that plays a crucial role in the biosynthesis of phosphatidylethanolamine, a key component of cell membranes, through the CDP-Etn pathway. ETNK1 monoclonal antibody (3F11) specifically recognizes an enzyme involved in catalyzing the phosphorylation of ethanolamine, which is essential for the production of phospholipids that maintain membrane integrity and fluidity. Proper functioning of ETNK1 is vital for cellular health, as disruptions in phosphatidylethanolamine synthesis can lead to various cellular dysfunctions and contribute to disease states. Localized primarily in the cytoplasm, ETNK1 is expressed in several human tissues, including the kidney, liver, placenta, heart, leukocyte, ovary, and testis, and exists in multiple isoforms due to alternative splicing. The gene encoding ETNK1 is located on human chromosome 12, a region associated with numerous genetic disorders, highlighting the importance of this protein in both normal physiology and disease.
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Ethanolamine kinase Antibody (3F11) References:
- Isolation and characterization of the Saccharomyces cerevisiae EKI1 gene encoding ethanolamine kinase. | Kim, K., et al. 1999. J Biol Chem. 274: 14857-66. PMID: 10329685
- Novel expression of equivocal messages containing both regions of choline/ethanolamine kinase and muscle type carnitine palmitoyltransferase I. | Yamazaki, N., et al. 2000. J Biol Chem. 275: 31739-46. PMID: 10918069
- Tissue-specific and developmental effects of the easily shocked mutation on ethanolamine kinase activity and phospholipid composition in Drosophila melanogaster. | Nyako, M., et al. 2001. Biochem Genet. 39: 339-49. PMID: 11758729
- Regulation of the yeast EKI1-encoded ethanolamine kinase by inositol and choline. | Kersting, MC., et al. 2004. J Biol Chem. 279: 35353-9. PMID: 15201274
- Ethanolamine kinase controls neuroblast divisions in Drosophila mushroom bodies. | Pascual, A., et al. 2005. Dev Biol. 280: 177-86. PMID: 15766757
- Regulation of the Saccharomyces cerevisiae EKI1-encoded ethanolamine kinase by zinc depletion. | Kersting, MC. and Carman, GM. 2006. J Biol Chem. 281: 13110-13116. PMID: 16551612
- Biochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei: the ethanolamine and choline kinases. | Gibellini, F., et al. 2008. Biochem J. 415: 135-44. PMID: 18489261
- Galactosemic cataractogenesis disrupts intracellular interactions and changes the substrate specificity of choline/ethanolamine kinase. | Liu, Y., et al. 1998. Exp Eye Res. 67: 193-202. PMID: 9733585
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ethanolamine kinase Antibody (3F11) | sc-517100 | 100 µg/ml | $322.00 |