Endothelin-1/EDN1/ET-1 Antibody (1C10): sc-57116
- Endothelin-1/EDN1/ET-1 Antibody (1C10) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 100 µg/ml
- raised against an N-terminus portion of ET-1 of human origin
- recommended for detection of ET-1 of human origin by ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Endothelin-1/EDN1/ET-1 Antibody (1C10). This work is in progress.
ET-1 Antibody (1C10) is a mouse monoclonal IgG1 antibody that detects endothelin-1 in human samples through enzyme-linked immunosorbent assay (ELISA). Endothelin-1 is a potent 21-amino acid vasoconstrictor peptide primarily produced by vascular endothelial cells, playing a crucial role in regulating vascular tone and blood pressure. Endothelin-1 function is vital as this peptide influences cardiovascular health, and dysregulation of endothelin-1 levels has been implicated in various pathological conditions, including hypertension and heart failure. Endothelin-1 production is tightly controlled, as this peptide is generated from a larger precursor known as big-endothelin through the action of endothelin-converting enzymes. Endothelin-1′s ability to induce vasoconstriction is mediated through interaction with specific receptor subtypes, ETA and ETB, which exhibit different affinities for the various endothelin isopeptides. Anti-endothelin-1 antibody (1C10) is an essential tool for researchers studying endothelin-1′s role in health and disease, providing insights into biological significance and potential therapeutic targets.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Endothelin-1/EDN1/ET-1 Antibody (1C10) | sc-57116 | 100 µg/ml | $322.00 |