Molecular structure of ESI-09, CAS Number: 263707-16-0
ESI-09 (CAS 263707-16-0)
Alternate Names:
ESI09 ESI 09 GTPL7917
CAS Number:
263707-16-0
Molecular Weight:
330.77
Molecular Formula:
C16H15ClN4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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ESI-09 (CAS 263707-16-0) References
- Lithium and an EPAC-specific inhibitor ESI-09 synergistically suppress pancreatic cancer cell proliferation and survival. | Wang, X., et al. 2017. Acta Biochim Biophys Sin (Shanghai). 49: 573-580. PMID: 28475672
- EPAC Regulates Melanoma Growth by Stimulating mTORC1 Signaling and Loss of EPAC Signaling Dependence Correlates with Melanoma Progression. | Krishnan, A., et al. 2022. Mol Cancer Res. 20: 1548-1560. PMID: 35834616
- A unique melanocortin-4-receptor signaling profile for obesity-associated constitutively active variants. | Botha, R., et al. 2023. J Mol Endocrinol. 71: PMID: 37040537
- Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development. | Boulton, S., et al. 2023. J Biol Chem. 299: 104749. PMID: 37100284
- EPAC1 inhibition protects the heart from doxorubicin-induced toxicity. | Mazevet, M., et al. 2023. Elife. 12: PMID: 37551870
- Upregulation of Epac1 Promotes Pericyte Loss by Inducing Mitochondrial Fission, Reactive Oxygen Species Production, and Apoptosis. | Yang, W., et al. 2023. Invest Ophthalmol Vis Sci. 64: 34. PMID: 37651112
- Bitter taste receptor (TAS2R) 46 in human skeletal muscle: expression and activity. | Talmon, M., et al. 2023. Front Pharmacol. 14: 1205651. PMID: 37771728
- Host cell cAMP-Epac-Rap1b pathway inhibition by hawthorn extract as a potential target against Trypanosoma cruzi infection. | Ferri, G., et al. 2023. Front Microbiol. 14: 1301862. PMID: 38156015
- EPAC inhibitor suppresses angiogenesis and tumor growth of triple-negative breast cancer. | Li, Z., et al. 2024. Biochim Biophys Acta Mol Basis Dis. 1870: 167114. PMID: 38447883
- Leishmania exploits host cAMP/EPAC/calcineurin signaling to induce an IL-33-mediated anti-inflammatory environment for the establishment of infection. | Roy, S., et al. 2024. J Biol Chem. 300: 107366. PMID: 38750790
Inhibitor of:
Epac, GPR101, MacroH2A1, Olfr1178, PECI, PRK2, and Rap 1A, RAP 1B.Activator of:
CREB, Rap 1A, and Vmn1r132.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ESI-09, 5 mg | sc-507491 | 5 mg | $230.00 |