ESE-1 Antibody (E-8): sc-376055
- ESE-1 Antibody (E-8) is a mouse monoclonal IgG1 κ ESE-1 antibody, cited in 5 publications, provided at 200 µg/ml
- raised against amino acids 1-270 mapping at the N-terminal of ESE-1 of human origin
- ESE-1 Antibody (E-8) is recommended for detection of ESE-1 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ESE-1 Antibody (E-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-376055 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ESE-1 Antibody (E-8) for WB and IHC(P) applications. These reagents are now offered in bundles with ESE-1 Antibody (E-8) (see ordering information below).
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ESE-1 Antibody (E-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects ESE-1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). ESE-1 (E-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ESE-1, a member of the Ets family of transcription factors, plays a crucial role in regulating epithelial cell differentiation and mediating vascular inflammation. ESE-1 is predominantly located in the vascular endothelium and smooth muscle cells, where ESE-1 expression is significantly induced by inflammatory cytokines and lipopolysaccharides. ESE-1′s interaction with NF-KappaB is particularly important, as this interaction leads to the induction of nitric oxide synthase, a key enzyme in vascular function and inflammation. Additionally, ESE-1 is upregulated during corneal epithelium differentiation and collaborates with Sp1 and AP-1 proteins to promote squamous differentiation marker expression in bronchial epithelial cells, highlighting ESE-1′s essential role in maintaining epithelial integrity and response to inflammatory stimuli.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ESE-1 Antibody (E-8) References:
- Ets family transcription factor ESE-1 is expressed in corneal epithelial cells and is involved in their differentiation. | Yoshida, N., et al. 2000. Mech Dev. 97: 27-34. PMID: 11025204
- ESE-1 is a novel transcriptional mediator of inflammation that interacts with NF-kappa B to regulate the inducible nitric-oxide synthase gene. | Rudders, S., et al. 2001. J Biol Chem. 276: 3302-9. PMID: 11036073
- Interplay between proximal and distal promoter elements is required for squamous differentiation marker induction in the bronchial epithelium: role for ESE-1, Sp1, and AP-1 proteins. | Reddy, SP., et al. 2003. J Biol Chem. 278: 21378-87. PMID: 12682075
- Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86. | Wang, H., et al. 2004. J Biol Chem. 279: 25241-50. PMID: 15075319
- The ETS transcription factor ESE-1 transforms MCF-12A human mammary epithelial cells via a novel cytoplasmic mechanism. | Prescott, JD., et al. 2004. Mol Cell Biol. 24: 5548-64. PMID: 15169914
- The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes. | Grall, FT., et al. 2005. FEBS J. 272: 1676-87. PMID: 15794755
- Ets transcription factors regulate AIRE gene promoter. | Murumägi, A., et al. 2006. Biochem Biophys Res Commun. 348: 768-74. PMID: 16890195
- Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family. | Oettgen, P., et al. 1997. Mol Cell Biol. 17: 4419-33. PMID: 9234700
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ESE-1 Antibody (E-8) | sc-376055 | 200 µg/ml | $322.00 | |||
ESE-1 Antibody (E-8): m-IgG Fc BP-HRP Bundle | sc-527503 | 200 µg Ab; 10 µg BP | $361.00 | |||
ESE-1 Antibody (E-8): m-IgG1 BP-HRP Bundle | sc-532876 | 200 µg Ab; 20 µg BP | $361.00 | |||
ESE-1 Antibody (E-8) X | sc-376055 X | 200 µg/0.1 ml | $322.00 | |||
ESE-1 Antibody (E-8) AC | sc-376055 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ESE-1 Antibody (E-8) HRP | sc-376055 HRP | 200 µg/ml | $322.00 | |||
ESE-1 Antibody (E-8) FITC | sc-376055 FITC | 200 µg/ml | $336.00 | |||
ESE-1 Antibody (E-8) PE | sc-376055 PE | 200 µg/ml | $349.00 | |||
ESE-1 Antibody (E-8) Alexa Fluor® 488 | sc-376055 AF488 | 200 µg/ml | $364.00 | |||
ESE-1 Antibody (E-8) Alexa Fluor® 546 | sc-376055 AF546 | 200 µg/ml | $364.00 | |||
ESE-1 Antibody (E-8) Alexa Fluor® 594 | sc-376055 AF594 | 200 µg/ml | $364.00 | |||
ESE-1 Antibody (E-8) Alexa Fluor® 647 | sc-376055 AF647 | 200 µg/ml | $364.00 | |||
ESE-1 Antibody (E-8) Alexa Fluor® 680 | sc-376055 AF680 | 200 µg/ml | $364.00 | |||
ESE-1 Antibody (E-8) Alexa Fluor® 790 | sc-376055 AF790 | 200 µg/ml | $364.00 |