ERRγ Antibody (D-1): sc-393969
- ERRγ Antibody (D-1) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 81-118 mapping near the N-terminus of ERRγ of human origin
- Anti-ERR gamma Antibody (D-1) is recommended for detection of ERRγ of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- Anti-ERR gamma Antibody (D-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-393969 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ERRγ Antibody (D-1) for WB applications. These reagents are now offered in bundles with ERRγ Antibody (D-1) (see ordering information below).
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SEE ALSO...
ERRγ Antibody (D-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects ERRγ in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ERRγ (D-1) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ERRγ, a member of the estrogen receptor-related family, plays a crucial role in regulating gene expression by binding to estrogen response elements (EREs), which are critical for transcriptional activation of genes involved in various physiological processes. Unlike traditional estrogen receptors, ERRγ functions as an orphan nuclear receptor, meaning ERRγ can activate ERE-containing genes independently of estrogen binding, thus influencing metabolic pathways and cellular differentiation. The predicted 436-amino acid ERRγ protein is primarily localized in the nucleus and is expressed in several tissues, including heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord, and thyroid gland, highlighting ERRγ′s importance in diverse biological functions across different organ systems.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ERRγ Antibody (D-1) References:
- Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3. | Hong, H., et al. 1999. J Biol Chem. 274: 22618-26. PMID: 10428842
- Human ERRgamma, a third member of the estrogen receptor-related receptor (ERR) subfamily of orphan nuclear receptors: tissue-specific isoforms are expressed during development and in the adult. | Heard, DJ., et al. 2000. Mol Endocrinol. 14: 382-92. PMID: 10707956
- Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3. | Greschik, H., et al. 2002. Mol Cell. 9: 303-13. PMID: 11864604
- Isolation of a gene encoding a novel member of the nuclear receptor superfamily from the critical region of Usher syndrome type IIa at 1q41. | Eudy, JD., et al. 1998. Genomics. 50: 382-4. PMID: 9676434
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ERRγ Antibody (D-1) | sc-393969 | 200 µg/ml | $316.00 | |||
ERRγ Antibody (D-1): m-IgG Fc BP-HRP Bundle | sc-530643 | 200 µg Ab; 10 µg BP | $354.00 | |||
ERRγ Antibody (D-1): m-IgGκ BP-HRP Bundle | sc-524159 | 200 µg Ab, 40 µg BP | $354.00 | |||
ERRγ Antibody (D-1): m-IgG1 BP-HRP Bundle | sc-544175 | 200 µg Ab; 20 µg BP | $354.00 | |||
ERRγ Antibody (D-1) X | sc-393969 X | 200 µg/0.1 ml | $316.00 | |||
ERRγ Antibody (D-1) AC | sc-393969 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ERRγ Antibody (D-1) HRP | sc-393969 HRP | 200 µg/ml | $316.00 | |||
ERRγ Antibody (D-1) FITC | sc-393969 FITC | 200 µg/ml | $330.00 | |||
ERRγ Antibody (D-1) PE | sc-393969 PE | 200 µg/ml | $343.00 | |||
ERRγ Antibody (D-1) Alexa Fluor® 488 | sc-393969 AF488 | 200 µg/ml | $357.00 | |||
ERRγ Antibody (D-1) Alexa Fluor® 546 | sc-393969 AF546 | 200 µg/ml | $357.00 | |||
ERRγ Antibody (D-1) Alexa Fluor® 594 | sc-393969 AF594 | 200 µg/ml | $357.00 | |||
ERRγ Antibody (D-1) Alexa Fluor® 647 | sc-393969 AF647 | 200 µg/ml | $357.00 | |||
ERRγ Antibody (D-1) Alexa Fluor® 680 | sc-393969 AF680 | 200 µg/ml | $357.00 | |||
ERRγ Antibody (D-1) Alexa Fluor® 790 | sc-393969 AF790 | 200 µg/ml | $357.00 |