Ep-CAM Antibody (AUA1): sc-53277
- Ep-CAM Antibody (AUA1) is a mouse monoclonal IgG1, cited in 4 publications, provided at 200 µg/ml
- raised against LoVo cell line of human origin
- Anti-Ep-CAM Antibody (AUA1) is recommended for detection of Ep-CAM of mouse, rat and human origin by WB, IP, IF and IHC(P)
- Anti-Ep-CAM Antibody (AUA1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Ep-CAM Antibody (AUA1). This work is in progress.
QUICK LINKS
SEE ALSO...
Ep-CAM Antibody (AUA1) is a mouse monoclonal IgG1 antibody that detects epithelial cell adhesion molecule (Ep-CAM) of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-Ep-CAM antibody (AUA1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Epithelial cell adhesion molecule, also known as tumor-associated calcium signal transducer 1 and MK-1, is a crucial monomeric membrane glycoprotein predominantly expressed in normal human epithelial tissues and various carcinomas. The human Ep-CAM gene encodes a 314 amino acid protein that exists in two forms, with the major form being significantly reduced when treated with the amino-glycosylation inhibitor tunicamycin. Ep-CAM is overexpressed in numerous carcinomas, making Ep-CAM a promising target for both visualization and therapeutic strategies in human solid tumors. The Ep-CAM structure features an extracellular domain with two epidermal growth factor-like repeats followed by a cysteine-poor region, which are essential for adhesive properties. These structural characteristics facilitate cell-cell adhesion and play a role in cellular signaling pathways, underscoring Ep-CAM′s significance in both normal physiology and cancer progression.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ep-CAM Antibody (AUA1) | sc-53277 | 200 µg/ml | $322.00 | |||
Ep-CAM Antibody (AUA1) AC | sc-53277 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Ep-CAM Antibody (AUA1) HRP | sc-53277 HRP | 200 µg/ml | $322.00 | |||
Ep-CAM Antibody (AUA1) FITC | sc-53277 FITC | 200 µg/ml | $336.00 | |||
Ep-CAM Antibody (AUA1) PE | sc-53277 PE | 200 µg/ml | $349.00 | |||
Ep-CAM Antibody (AUA1) Alexa Fluor® 488 | sc-53277 AF488 | 200 µg/ml | $364.00 | |||
Ep-CAM Antibody (AUA1) Alexa Fluor® 546 | sc-53277 AF546 | 200 µg/ml | $364.00 | |||
Ep-CAM Antibody (AUA1) Alexa Fluor® 594 | sc-53277 AF594 | 200 µg/ml | $364.00 | |||
Ep-CAM Antibody (AUA1) Alexa Fluor® 647 | sc-53277 AF647 | 200 µg/ml | $364.00 | |||
Ep-CAM Antibody (AUA1) Alexa Fluor® 680 | sc-53277 AF680 | 200 µg/ml | $364.00 | |||
Ep-CAM Antibody (AUA1) Alexa Fluor® 790 | sc-53277 AF790 | 200 µg/ml | $364.00 |