Enolase Antibody (5A4): sc-51880
- Enolase Antibody (5A4) is a mouse monoclonal IgG2a, cited in 7 publications, provided at 100 µg/ml
- raised against purified neuron-specific neuron-specific Enolase from human brain
- recommended for detection of neuron-specific enolase of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See Enolase (A-5): sc-271384 for Enolase antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Enolase Antibody (5A4). This work is in progress.
Enolase Antibody (5A4) is a mouse monoclonal IgG2a antibody that detects enolase in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Enolase is a crucial enzyme in the glycolytic pathway, facilitating the conversion of 2-phosphoglycerate to phosphoenolpyruvate, a key step in energy production. This process is vital for cellular metabolism, particularly in tissues with high energy demands, such as muscle and brain. The enzyme exists in three isoforms—α, β, and γ enolase—each with distinct tissue distribution and functional roles. While α enolase is widely expressed across various tissues, β enolase is predominantly found in muscle, and γ enolase is specific to nervous tissue. The presence of these isoforms as both homodimers and heterodimers allows for functional versatility, adapting to the metabolic needs of different cell types. α enolase shares significant homology with yeast enolase and rat nonneural enolase, highlighting evolutionary conservation. Additionally, α enolase is encoded by the same gene as tau-crystallin, a structural protein in the lens, linking metabolic function to structural integrity in ocular tissues. Anti-enolase antibody (5A4) serves as an essential tool for researchers studying glycolysis and its implications in various physiological and pathological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Enolase Antibody (5A4) | sc-51880 | 100 µg/ml | $316.00 |