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Endophilin B2 Antibody (E-2): sc-393989

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Datasheets
  • Endophilin B2 Antibody (E-2) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 349-374 at the C-terminus of Endophilin B2 of human origin
  • recommended for detection of all isoforms of Endophilin B2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
  • m-IgG3 BP-HRP is the preferred secondary detection reagent for Endophilin B2 Antibody (E-2) for WB applications. This reagent is now offered in a bundle with Endophilin B2 Antibody (E-2) (see ordering information below).

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    Endophilin B2 Antibody (E-2) is a mouse monoclonal IgG3 antibody that detects Endophilin B2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Endophilin B2 plays a crucial role in the regulation of synaptic vesicle trafficking and is essential for maintaining the dynamics of the outer mitochondrial membrane, which is vital for cellular energy production and apoptosis regulation. Endophilin B2 is predominantly expressed in the brain, adult lung, ovary, and spinal cord, highlighting its importance in neuronal function and development. Notably, decreased levels of Endophilin B2 have been associated with Down Syndrome, suggesting that alterations in expression may contribute to brain dysgenesis and other neurological disorders. Anti-Endophilin B2 antibody (E-2) is an invaluable tool for researchers investigating the molecular mechanisms underlying synaptic function and mitochondrial dynamics, providing insights into both normal physiology and disease states.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Endophilin B2 Antibody (E-2)

    sc-393989
    200 µg/ml
    $316.00

    Endophilin B2 Antibody (E-2): m-IgG3 BP-HRP Bundle

    sc-550501
    200 µg Ab; 40 µg BP
    $354.00

    Endophilin B2 (E-2) Neutralizing Peptide

    sc-393989 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-393989 P appropriate for?

    Asked by: Professor Griffin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 5 out of 5 by from Satisfactory Western blot data of EndophilinSatisfactory Western blot data of Endophilin B2 expression in non-transfected and human Endophilin B2 transfected 293T whole cell lysates. -SCBT QC
    Date published: 2013-05-05
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    Endophilin B2 Antibody (E-2) is rated 5.0 out of 5 by 1.
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