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Endoglin/CD105 Antibody (MJ7/18): sc-18893

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Datasheets
  • Endoglin/CD105 Antibody (MJ7/18) is a rat monoclonal IgG2a, cited in 13 publications, provided at 200 µg/ml
  • raised against inflamed mouse skin tissue
  • recommended for detection of Endoglin of mouse, rat and human origin by WB, IP, IF and FCM
  • available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • See Endoglin/CD105 (P3D1): sc-18838 for Endoglin/CD105 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Endoglin/CD105 Antibody (MJ7/18). This work is in progress.

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SEE ALSO...

Endoglin Antibody (MJ7/18) is a rat monoclonal IgG2a antibody that detects Endoglin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Endoglin plays a crucial role in vascular development and homeostasis, as a co-receptor for transforming growth factor-beta (TGF-β) superfamily ligands, which are essential for endothelial cell function and angiogenesis. Endoglin modulates signaling pathways that regulate blood vessel formation and repair, making Endoglin a key player in maintaining vascular integrity. Mutations in the Endoglin gene are associated with hereditary hemorrhagic telangiectasia (HHT), a disorder characterized by abnormal blood vessel formation and increased risk of bleeding. By understanding Endoglin function and interactions with TGF-β ligands, researchers can gain insights into mechanisms underlying vascular diseases and develop potential therapeutic strategies. Endoglin monoclonal antibody (MJ7/18) is an invaluable tool for studying these processes and advancing our knowledge of vascular biology.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Endoglin/CD105 Antibody (MJ7/18)

sc-18893
200 µg/ml
$316.00

Endoglin/CD105 Antibody (MJ7/18) FITC

sc-18893 FITC
200 µg/ml
$330.00

Endoglin/CD105 Antibody (MJ7/18) PE

sc-18893 PE
200 µg/ml
$343.00

Can Endoglin (MJ7/18): sc-18893 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: cjMara
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, Endoglin (MJ7/18): sc-18893 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by from WB with mouse kidney extractsWB with mouse kidney extracts. -SCBT Publication Review
Date published: 2015-05-27
Rated 3 out of 5 by from IF with murine uterus sectionsIF with murine uterus sections. -SCBT Publication Review
Date published: 2015-05-26
Rated 4 out of 5 by from Published Flow Cytometry data using murinePublished Flow Cytometry data using murine embryonic endothelial cells. -SCBT Publication Review
Date published: 2015-05-16
Rated 3 out of 5 by from Decent immunofluorescence membrane stainingDecent immunofluorescence membrane staining in methanol-fixed JAR cells. -SCBT QC
Date published: 2015-03-31
Rated 3 out of 5 by from Used for immunohistochemical analysis ofUsed for immunohistochemical analysis of paraffin embedded human testes sections. -SCBT Publication Review
Date published: 2015-02-24
Rated 3 out of 5 by from Satisfactory FCM data of mouse peripheralSatisfactory FCM data of mouse peripheral blood leukocytes. -SCBT QC
Date published: 2013-03-15
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Endoglin/CD105 Antibody (MJ7/18) is rated 3.3 out of 5 by 6.
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