EMMPRIN/CD147 Antibody (RL73): sc-53862

EMMPRIN Antibody (RL73) is a rat monoclonal IgG2a antibody that detects EMMPRIN in mouse samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and flow cytometry (FCM). EMMPRIN, also known as basigin or CD147, plays a crucial role in the regulation of matrix remodeling at the epidermal-dermal interface, where anti-EMMPRIN antibody (RL73) stimulates fibroblasts to produce key enzymes such as interstitial collagenase, gelatinase A, and stromelysin-1, along with various metalloproteinases (MMPs). These enzymes are particularly significant during tissue degradation and wound healing, as they facilitate the breakdown and remodeling of the extracellular matrix. EMMPRIN′s importance extends to cancer biology, where the upregulation of these MMPs contributes to cancer invasion and metastasis, making EMMPRIN (RL73) monoclonal antibody a vital target for understanding tumor progression and developing therapeutic strategies. EMMPRIN (RL73) antibody serves as an essential tool for researchers investigating the dynamics of extracellular matrix interactions and their implications in both normal physiological processes and pathological conditions.

The preferred EMMPRIN/CD147 antibody is EMMPRIN/CD147 Antibody (8D6): sc-21746.