EMID2 Antibody (B-7): sc-514522
- EMID2 Antibody (B-7) is a mouse monoclonal IgG2a κ EMID2 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 377-402 near the C-terminus of EMID2 of human origin
- EMID2 Antibody (B-7) is recommended for detection of EMID2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-EMID2 Antibody (B-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for EMID2 Antibody (B-7) for WB applications. These reagents are now offered in bundles with EMID2 Antibody (B-7) (see ordering information below).
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EMID2 Antibody (B-7) is a mouse monoclonal IgG2a kappa light chain antibody that detects EMID2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-EMID2 antibody (B-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. EMID2, also known as EMI domain-containing protein 2 or COL26A1, is a 441 amino acid secreted protein that plays a crucial role in extracellular matrix organization and tissue development. EMID2 is characterized by a unique structure that includes an N-terminal signal peptide, an EMI domain, two collagen stretches, and a novel C-terminal domain. The EMI domain contains seven conserved cysteines that may facilitate dimerization, which is essential for functional stability and interaction with other extracellular matrix components. EMID2 undergoes post-translational modifications, including hydroxylation on proline residues, which can influence stability and interactions. EMID2 is conserved across several species, including chimpanzees, dogs, cows, mice, and chickens, and is located on human chromosome 7q22.1, which is associated with various genetic disorders. Understanding EMID2′s function and structure is vital for elucidating its role in developmental processes and potential implications in diseases related to extracellular matrix dysregulation.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
EMID2 Antibody (B-7) References:
- Type XXVI collagen, a new member of the collagen family, is specifically expressed in the testis and ovary. | Sato, K., et al. 2002. J Biol Chem. 277: 37678-84. PMID: 12145293
- Developmental expression and biochemical characterization of Emu family members. | Leimeister, C., et al. 2002. Dev Biol. 249: 204-18. PMID: 12221002
- The DNA sequence of human chromosome 7. | Hillier, LW., et al. 2003. Nature. 424: 157-64. PMID: 12853948
- Structural aberrations of chromosome 7 revealed by a combination of molecular cytogenetic techniques in myeloid malignancies. | Brezinová, J., et al. 2007. Cancer Genet Cytogenet. 173: 10-6. PMID: 17284364
- Molecular anatomy of chromosome 7q deletions in myeloid neoplasms: evidence for multiple critical loci. | Liang, H., et al. 1998. Proc Natl Acad Sci U S A. 95: 3781-5. PMID: 9520444
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EMID2 Antibody (B-7) | sc-514522 | 200 µg/ml | $322.00 | |||
EMID2 Antibody (B-7): m-IgGκ BP-HRP Bundle | sc-524753 | 200 µg Ab, 40 µg BP | $361.00 | |||
EMID2 Antibody (B-7): m-IgG2a BP-HRP Bundle | sc-546173 | 200 µg Ab; 10 µg BP | $361.00 | |||
EMID2 Antibody (B-7) AC | sc-514522 AC | 500 µg/ml, 25% agarose | $424.00 | |||
EMID2 Antibody (B-7) HRP | sc-514522 HRP | 200 µg/ml | $322.00 | |||
EMID2 Antibody (B-7) FITC | sc-514522 FITC | 200 µg/ml | $336.00 | |||
EMID2 Antibody (B-7) PE | sc-514522 PE | 200 µg/ml | $349.00 | |||
EMID2 Antibody (B-7) Alexa Fluor® 488 | sc-514522 AF488 | 200 µg/ml | $364.00 | |||
EMID2 Antibody (B-7) Alexa Fluor® 546 | sc-514522 AF546 | 200 µg/ml | $364.00 | |||
EMID2 Antibody (B-7) Alexa Fluor® 594 | sc-514522 AF594 | 200 µg/ml | $364.00 | |||
EMID2 Antibody (B-7) Alexa Fluor® 647 | sc-514522 AF647 | 200 µg/ml | $364.00 | |||
EMID2 Antibody (B-7) Alexa Fluor® 680 | sc-514522 AF680 | 200 µg/ml | $364.00 | |||
EMID2 Antibody (B-7) Alexa Fluor® 790 | sc-514522 AF790 | 200 µg/ml | $364.00 | |||
EMID2 (B-7) Neutralizing Peptide | sc-514522 P | 100 µg/0.5 ml | $69.00 |