Embigin Antibody (43G7): sc-130919
- Embigin Antibody (43G7) is a rat monoclonal IgG2b Embigin antibody provided at 200 µg/ml
- raised against CHO cells transfected with Embigin of mouse origin
- Embigin Antibody (43G7) is recommended for detection of Embigin of mouse origin by IF and FCM
- Anti-Embigin Antibody (43G7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Embigin Antibody (43G7). This work is in progress.
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Embigin Antibody (43G7) is a rat monoclonal IgG2b antibody that detects Embigin protein of mouse origin by immunofluorescence (IF) and flow cytometry (FCM). Anti-Embigin antibody (43G7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Embigin, also known as teratocarcinoma glycoprotein Gp-70, is a 327 amino acid single-pass type I membrane protein that belongs to the immunoglobulin superfamily of cell adhesion molecules. Embigin facilitates cell growth and development by regulating interactions between cells and the extracellular matrix, which is crucial for maintaining tissue homeostasis in normal adult tissues. Embigin is expressed in various adult tissues, including the brain, heart, liver, and lung, and plays a significant role during the regression of prostate and mammary glands. Embigin is involved in the modulation of neuromuscular junction formation and plasticity, highlighting its importance in both developmental and regenerative processes. The gene encoding Embigin is located on human chromosome 5q11.1, with a pseudogene identified on chromosome 1, further emphasizing the complexity of its genetic regulation and potential implications in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Embigin Antibody (43G7) References:
- Genomic organization and promoter activity of embigin, a member of the immunoglobulin superfamily. | Tachikui, H., et al. 1999. Gene. 240: 325-32. PMID: 10580152
- A novel role for embigin to promote sprouting of motor nerve terminals at the neuromuscular junction. | Lain, E., et al. 2009. J Biol Chem. 284: 8930-9. PMID: 19164284
- Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. | Wollscheid, B., et al. 2009. Nat Biotechnol. 27: 378-86. PMID: 19349973
- A teratocarcinoma glycoprotein carrying a developmentally regulated carbohydrate marker is a member of the immunoglobulin gene superfamily. | Ozawa, M., et al. 1988. J Biol Chem. 263: 3059-62. PMID: 2963822
- Embigin, a member of the immunoglobulin superfamily expressed in embryonic cells, enhances cell-substratum adhesion. | Huang, RP., et al. 1993. Dev Biol. 155: 307-14. PMID: 8432389
- Isolation and characterization of genes associated with chromosome-6 mediated tumor suppression in human malignant melanoma. | Ray, ME., et al. 1996. Oncogene. 12: 2527-33. PMID: 8700511
- Embigin, a developmentally expressed member of the immunoglobulin super family, is also expressed during regression of prostate and mammary gland. | Guenette, RS., et al. 1997. Dev Genet. 21: 268-78. PMID: 9438341
- Embigin/basigin subgroup of the immunoglobulin superfamily: different modes of expression during mouse embryogenesis and correlated expression with carbohydrate antigenic markers. | Fan, QW., et al. 1998. Dev Growth Differ. 40: 277-86. PMID: 9639355
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Embigin Antibody (43G7) | sc-130919 | 200 µg/ml | $316.00 | |||
Embigin Antibody (43G7) AC | sc-130919 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Embigin Antibody (43G7) HRP | sc-130919 HRP | 200 µg/ml | $316.00 | |||
Embigin Antibody (43G7) FITC | sc-130919 FITC | 200 µg/ml | $330.00 | |||
Embigin Antibody (43G7) PE | sc-130919 PE | 200 µg/ml | $343.00 | |||
Embigin Antibody (43G7) Alexa Fluor® 488 | sc-130919 AF488 | 200 µg/ml | $357.00 | |||
Embigin Antibody (43G7) Alexa Fluor® 546 | sc-130919 AF546 | 200 µg/ml | $357.00 | |||
Embigin Antibody (43G7) Alexa Fluor® 594 | sc-130919 AF594 | 200 µg/ml | $357.00 | |||
Embigin Antibody (43G7) Alexa Fluor® 647 | sc-130919 AF647 | 200 µg/ml | $357.00 | |||
Embigin Antibody (43G7) Alexa Fluor® 680 | sc-130919 AF680 | 200 µg/ml | $357.00 | |||
Embigin Antibody (43G7) Alexa Fluor® 790 | sc-130919 AF790 | 200 µg/ml | $357.00 |