eIF1AY Antibody (1B4): sc-517065

eIF1AY Antibody (1B4) is a mouse monoclonal IgG2a kappa light chain antibody that detects eIF1AY protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-eIF1AY antibody (1B4) is available as a non-conjugated format. eIF1AY protein, also known as eukaryotic translation initiation factor 1A, Y-chromosomal, plays a crucial role in protein synthesis initiation, essential for cellular function and growth. eIF1AY (1B4) antibody targets a protein involved in ribosomal subunit assembly, specifically facilitating 40S subunit binding to mRNA start codon, ensuring correct amino acid sequence synthesis. This process is vital for producing proteins that perform various cellular functions, including enzymatic activity, structural roles, and signaling pathways. eIF1AY is encoded by a gene in the non-recombining Y chromosome region in humans and on chromosome 18 in mice and rats, highlighting evolutionary significance and potential implications in sex-linked genetic studies. eIF1AY consists of 144 amino acids with a single S1-like domain, important for interaction with other translation factors. eIF1AY′s role in enhancing protein biosynthesis underscores its importance in cellular metabolism and growth, making it valuable for developmental biology and disease mechanism research.

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eIF1AY Antibody (1B4) References:

1. Screening for microdeletions of Y chromosome genes in patients undergoing intracytoplasmic sperm injection.  |  Krausz, C., et al. 1999. Hum Reprod. 14: 1717-21. PMID: 10402374
2. Expression analysis of thirty one Y chromosome genes in human prostate cancer.  |  Lau, YF. and Zhang, J. 2000. Mol Carcinog. 27: 308-21. PMID: 10747295
3. Expression profile of AZF genes in testicular biopsies of azoospermic men.  |  Kleiman, SE., et al. 2007. Hum Reprod. 22: 151-8. PMID: 16936303
4. Functional coherence of the human Y chromosome.  |  Lahn, BT. and Page, DC. 1997. Science. 278: 675-80. PMID: 9381176

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-eIF1AY Antibody (1B4) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-eIF1AY Antibody (1B4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

eIF1AY Antibody (1B4) Specifications

Alternate Product Name: eIF1AY

Product Clone Name: 1B4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 22-95

Epitope Target: eIF1AY

Epitope Species: human

Product Reactivity/Detection: eIF1AY

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for eIF1AY Antibody (1B4): N/A