EHD3 Antibody (RR-L): sc-100723

EHD3 Antibody (RR-L) is a mouse monoclonal IgG1 kappa light chain antibody that detects EHD3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-EHD3 antibody (RR-L) is available as the non-conjugated format. The Eps15 homology (EH) domain-containing protein family, which includes EHD1, EHD2, EHD3, and EHD4, plays a crucial role in cellular processes such as endocytosis and membrane trafficking. EHD3 is predominantly expressed in the brain, kidney, liver, placenta, ovary, and heart, highlighting its importance in various physiological functions. EHD3 structure features multiple conserved regions, including an amino-terminal nucleotide-binding consensus site and a carboxy-terminal EH protein-binding domain, which are essential for interaction with other proteins and cellular components. EHD3 is involved in the regulation of endocytic pathways, which are vital for nutrient uptake and receptor recycling, thereby influencing cellular signaling and homeostasis. Understanding EHD3 function and interactions can provide insights into its role in health and disease, making anti-EHD3 antibody (RR-L) a valuable tool for researchers studying these processes.

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EHD3 Antibody (RR-L) References:

1. EHD1--an EH-domain-containing protein with a specific expression pattern.  |  Mintz, L., et al. 1999. Genomics. 59: 66-76. PMID: 10395801
2. Evaluation and molecular characterization of EHD1, a candidate gene for Bardet-Biedl syndrome 1 (BBS1).  |  Haider, NB., et al. 1999. Gene. 240: 227-32. PMID: 10564830
3. EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins.  |  Pohl, U., et al. 2000. Genomics. 63: 255-62. PMID: 10673336
4. Characterization of EHD4, an EH domain-containing protein expressed in the extracellular matrix.  |  Kuo, HJ., et al. 2001. J Biol Chem. 276: 43103-10. PMID: 11533061
5. A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane.  |  Caplan, S., et al. 2002. EMBO J. 21: 2557-67. PMID: 12032069
6. EHD3: a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1.  |  Galperin, E., et al. 2002. Traffic. 3: 575-89. PMID: 12121420

The preferred EHD antibody is EHD Antibody (E-5): sc-271658.