EGFL8 Antibody (F-6): sc-377016

EGFL8 Antibody (F-6) is a mouse monoclonal IgM antibody that detects EGFL8 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-EGFL8 antibody (F-6) is available as a non-conjugated format. EGFL8, also known as C6orf8, NG3, and VE-statin-2, is a 293 amino acid secreted protein characterized by two EGF-like domains and one EMI domain, which are crucial for mediating protein-protein interactions. These interactions play a vital role in cellular proliferation and developmental signaling pathways, influencing various biological processes. EGFL8 expression is predominantly observed in brain, kidney, lung, and thymus of mice, highlighting importance in organ-specific functions and potential implications in developmental biology and disease states. Anti-EGFL8 antibody (F-6) enables exploration of EGFL8′s roles in cellular dynamics and potential as a biomarker in various conditions.

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EGFL8 Antibody (F-6) References:

1. EMI domains are widespread and reveal the probable orthologs of the Caenorhabditis elegans CED-1 protein.  |  Callebaut, I., et al. 2003. Biochem Biophys Res Commun. 300: 619-23. PMID: 12507493
2. Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.  |  Xie, T., et al. 2003. Genome Res. 13: 2621-36. PMID: 14656967
3. Egfl7, a novel epidermal growth factor-domain gene expressed in endothelial cells.  |  Fitch, MJ., et al. 2004. Dev Dyn. 230: 316-24. PMID: 15162510
4. Signal peptide prediction based on analysis of experimentally verified cleavage sites.  |  Zhang, Z. and Henzel, WJ. 2004. Protein Sci. 13: 2819-24. PMID: 15340161
5. The many faces of epidermal growth factor repeats.  |  Davis, CG. 1990. New Biol. 2: 410-9. PMID: 2288911
6. Structure and function of epidermal growth factor-like regions in proteins.  |  Appella, E., et al. 1988. FEBS Lett. 231: 1-4. PMID: 3282918

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-EGFL8 Antibody (F-6) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-EGFL8 Antibody (F-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

EGFL8 Antibody (F-6) Specifications

Alternate Product Name: EGFL8

Product Clone Name: F-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 271-293

Epitope Target: EGFL8

Epitope Species: human

Product Reactivity/Detection: EGFL8

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for EGFL8 Antibody (F-6): P: Blocking Peptide