EFP Antibody (E-12): sc-271254
- EFP Antibody (E-12) is a mouse monoclonal IgG3 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 150-175 near the N-terminus of EFP of human origin
- recommended for detection of EFP of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- TransCruz reagent for ChIP application (sc-271254 X, 200 µg/0.1 ml)
- m-IgG3 BP-HRP is the preferred secondary detection reagent for EFP Antibody (E-12) for WB and IHC(P) applications. This reagent is now offered in a bundle with EFP Antibody (E-12) (see ordering information below).
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SEE ALSO...
EFP Antibody (E-12) is a mouse monoclonal IgG3 antibody that detects EFP (estrogen-responsive finger protein) in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). EFP plays a crucial role as a transcription factor regulated by estrogen, a hormone essential for numerous physiological processes. EFP is a member of the RING finger family, characterized by a zinc-binding domain, and features two B box domains along with a coiled-coil region that serves as a transactivation domain. The structural composition of EFP allows for precise interaction with estrogen receptors, facilitating transcriptional regulation of target genes in response to estrogen signaling. This interaction is vital for growth, differentiation, and function of various tissues, highlighting EFP′s importance in mediating estrogen′s effects. The regulation of EFP gene expression involves multiple promoter elements and interacting factors, which underscores EFP′s role in a broader signaling cascade that influences secondary estrogen-responsive genes. Anti-EFP antibody (E-12) is an essential tool for researchers investigating molecular mechanisms of estrogen signaling and implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EFP Antibody (E-12) | sc-271254 | 200 µg/ml | $316.00 | |||
EFP Antibody (E-12): m-IgG3 BP-HRP Bundle | sc-550400 | 200 µg Ab; 40 µg BP | $354.00 | |||
EFP (E-12) Neutralizing Peptide | sc-271254 P | 100 µg/0.5 ml | $68.00 | |||
EFP Antibody (E-12) X | sc-271254 X | 200 µg/0.1 ml | $316.00 |