EFP Antibody (2): sc-135893
- EFP Antibody (2) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
- raised against amino acids 32-210 of EFP of human origin
- recommended for detection of EFP of human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for EFP Antibody (2). This work is in progress.
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SEE ALSO...
EFP Antibody (2) is a mouse monoclonal IgG1 antibody that detects estrogen-responsive finger protein (EFP) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). EFP is a crucial transcription factor that plays a significant role in mediating estrogen signaling, which is vital for the growth, differentiation, and function of various target cells across different tissues. As a member of the RING finger protein family, EFP features a unique structure that includes a Zn2+ binding domain, two B box domains, and a coiled-coil region that serves as a transactivation domain. This structural composition enables EFP to interact with other proteins and regulatory elements, thereby influencing gene expression in response to estrogen. EFP is involved in a signaling cascade where estrogen binds to its receptor, leading to the upregulation of EFP gene expression, which in turn activates the transcription of secondary estrogen-responsive genes. The regulation of EFP involves multiple elements and their interacting factors, highlighting EFP′s importance in the intricate network of hormonal regulation and potential implications in various physiological and pathological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EFP Antibody (2) | sc-135893 | 50 µg/0.5 ml | $322.00 |