
EF-1 γ Antibody (X5-P) is a mouse monoclonal IgG1 antibody that detects EF-1 γ in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). EF-1 γ, also known as EEF1G or GIG35, is a crucial 437 amino acid subunit of the elongation factor-1 complex, which plays a vital role in protein synthesis by facilitating the delivery of aminoacyl-tRNAs to the ribosome. EF-1 γ is predominantly expressed in various tissues, including the stomach, pancreas, brain, lung, kidney, intestine, liver, and spleen, highlighting its importance in diverse biological processes. Notably, EF-1 γ contains an N-terminal glutathione transferase domain that anchors the complex to different cellular components, thereby influencing the assembly of multiprotein complexes that include aminoacyl-tRNA synthetases. Increased expression levels of EF-1 γ have been linked to pancreatic cancer, suggesting a potential role in oncogenic transformation. Anti-EF-1 γ antibody (X5-P) serves as an essential tool for researchers investigating the molecular mechanisms underlying protein synthesis and its implications in cancer biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EF-1 γ Antibody (X5-P) | sc-101035 | 100 µg/ml | $339.00 |