EF-1 β Antibody (3A5): sc-517178

EF-1 β Antibody (3A5) is a mouse monoclonal IgG2a kappa light chain antibody that detects EF-1 beta protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-EF-1 beta antibody (3A5) is available as a non-conjugated format. The EF-1 protein complex plays a crucial role in protein synthesis by facilitating the delivery of aminoacyl-tRNAs to the ribosome, a process essential for translating genetic information into functional proteins. This complex is composed of four subunits: EF-1 α, EF-1 β, EF-1 δ, and EF-1 γ, with EF-1 β being a 225 amino acid protein that belongs to the EF-1 β/EF-1 δ family and features a GST C-terminal domain. Notably, EF-1 β and EF-1 δ are involved in the GDP to GTP exchange on EF-1 α, a critical step in the elongation phase of translation. The phosphorylation status of EF-1 β significantly influences the GDP/GTP exchange rate, thereby impacting the efficiency of protein synthesis. Alternative splicing of the gene encoding EF-1 β results in three transcript variants that differ in their 5′ untranslated regions, which may have implications for the regulation of its expression and function.

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EF-1 β Antibody (3A5) References:

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