Edc3 Antibody (B-9): sc-271732
- Edc3 Antibody (B-9) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 209-508 mapping at the C-terminus of Edc3 of human origin
- recommended for detection of Edc3 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Edc3 Antibody (B-9) for WB applications. These reagents are now offered in bundles with Edc3 Antibody (B-9) (see ordering information below).
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Edc3 Antibody (B-9) is a mouse monoclonal IgG2b antibody that detects Edc3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Edc3, or enhancer of mRNA-decapping protein 3, is a crucial 508 amino acid protein encoded by the human gene EDC3, and plays a significant role in the regulation of mRNA decay, a vital process for maintaining cellular homeostasis and gene expression. Edc3 is primarily localized in the cytoplasm, particularly within processing bodies (PBs), where Edc3 participates in the mRNA degradation pathway by forming a complex with other key proteins, including hDcp1a, hDcp2a, RCK, and Edc4/HEDLS. The interaction of Edc3 with DCP1A and DDX6 is essential for the decapping process, which serves as a critical control point in mRNA turnover. Additionally, Edc3 has been shown to interact with TTP (zinc finger protein 36), a protein implicated in obesity-related metabolic complications, highlighting Edc3′s potential role in metabolic regulation. Anti-Edc3 antibody (B-9) is an invaluable tool for researchers studying mRNA decay mechanisms and their implications in various biological processes and diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Edc3 Antibody (B-9) | sc-271732 | 200 µg/ml | $322.00 | |||
Edc3 Antibody (B-9): m-IgGκ BP-HRP Bundle | sc-535036 | 200 µg Ab; 40 µg BP | $361.00 | |||
Edc3 Antibody (B-9): m-IgG2b BP-HRP Bundle | sc-549334 | 200 µg Ab; 10 µg BP | $361.00 |