Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
B lymphocyte maturation is an intricate process that requires a distinct set of transcription factors with respect to the stage of cell differentiation and cell lineage. Among the transcriptional regulators involved in the early stages of B cell development, early B cell factor (EBF), also designated olfactory neuronal transcription factor 1 (OLF1), targets promoter elements for B lymphoid kinase (Blk) and genes encoding portions of the early stage B cell receptors (BCR), which are necessary for initiation of Ig light chain gene recombination and Src kinase (Blk) signaling. EBF is a basic helix-loop-helix (bHLH) homodimeric transcription factor composed of two subunits that interact with the core DNA sequence, CCCNNGGG, through a DNA recognition domain containing a zinc-coordination motif. Promoter elements to certain neuron-specific genes encoding olfactory-related proteins have been shown to contain EBF binding sites.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.