EAG Antibody (C-4): sc-377349

EAG Antibody (C-4) is a mouse monoclonal IgG1 antibody that detects EAG protein of Streptococcus equi by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-EAG antibody (C-4) specifically targets EAG protein, which is a 429 amino acid molecule known for its role in binding immunoglobulins, α2-macroglobulin, and albumin, thereby playing a crucial part in the immune evasion strategies of S. equi. EAG protein′s ability to interact with host immune components is vital, as S. equi can persist and cause the highly contagious disease known as strangles, which primarily affects young horses with underdeveloped immune systems. EAG presence in the extracellular environment of S. equi facilitates the onset of a profound inflammatory response in the host, characterized by symptoms such as lymphadenopathy, fever, nasal discharge, and anorexia. Using EAG (C-4) antibody in various applications helps researchers gain insights into infection mechanisms and host-pathogen interactions that contribute to strangles pathogenesis, ultimately aiding in the development of effective treatments and preventive measures against this significant equine disease.

The preferred EAG antibody is EAG Antibody (C-9): sc-377236.