EAG Antibody (A-1): sc-377237
- EAG Antibody (A-1) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 215-429 of EAG of Streptococcus equi subsp. equi origin
- recommended for detection of of S. equi origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for EAG Antibody (A-1). This work is in progress.
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SEE ALSO...
EAG Antibody (A-1) is a mouse monoclonal IgG2a antibody that detects EAG protein of Streptococcus equi by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-EAG antibody (A-1) specifically targets EAG protein, a 429 amino acid molecule known for its critical role in the pathogenesis of strangles, a highly contagious disease affecting horses. EAG protein is primarily located on the surface of S. equi, where EAG plays a vital role in evading the host′s immune response, thereby facilitating bacterial survival and proliferation within the host. EAG binding to host proteins, such as alpha2-macroglobulin and albumin, allows the pathogen to manipulate the host′s immune system, leading to severe inflammatory responses and clinical symptoms like lymphadenopathy, fever, and nasal discharge. Understanding EAG protein function and interactions is crucial for developing effective treatments and vaccines against strangles, making EAG monoclonal antibody (A-1) an invaluable tool for researchers studying this significant equine health issue.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EAG Antibody (A-1) | sc-377237 | 200 µg/ml | $316.00 |