E-Selectin/CD62E/SELE Antibody (A-10): sc-137203
- E-Selectin/CD62E/SELE Antibody (A-10) is a mouse monoclonal IgG1 κ, cited in 7 publications, provided at 200 µg/ml
- raised against amino acids 311-610 mapping at the C-terminus of E-Selectin of human origin
- recommended for detection of E-Selectin of human origin by WB, IP, IF and ELISA
- See E-Selectin/CD62E/SELE (D-7): sc-137054 for E-Selectin/CD62E/SELE antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for E-Selectin/CD62E/SELE Antibody (A-10) for WB applications. These reagents are now offered in bundles with E-Selectin/CD62E/SELE Antibody (A-10) (see ordering information below).
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E-Selectin Antibody (A-10) is a mouse monoclonal IgG1 antibody that detects E-Selectin in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). E-Selectin, also known as ELAM-1 or CD62E, is a crucial adhesion molecule expressed on the surface of endothelial cells in response to pro-inflammatory cytokines. Anti-E-Selectin antibody (A-10) recognizes a protein that mediates the adhesion of leukocytes to the vascular endothelium during inflammatory responses, which is vital for the recruitment of immune cells to sites of injury or infection. E-Selectin′s ability to facilitate this process is essential for effective immune surveillance and response, as this mechanism helps ensure leukocytes can exit the bloodstream and migrate to tissues where needed. E-Selectin′s interaction with specific carbohydrates on leukocytes underscores a role in the complex signaling pathways that regulate inflammation and immune responses. Anti-E-Selectin antibody (A-10) serves as an invaluable tool for researchers studying these critical processes in human health and disease.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
E-Selectin/CD62E/SELE Antibody (A-10) References:
- E-selectin modulates the malignant properties of T84 colon carcinoma cells. | Flugy, AM., et al. 2002. Biochem Biophys Res Commun. 293: 1099-106. PMID: 12051773
- L-selectin serves as an E-selectin ligand on cultured human T lymphoblasts. | Jutila, MA., et al. 2002. J Immunol. 169: 1768-73. PMID: 12165498
- E-Selectin mediates pathogenic effects of antiphospholipid antibodies. | Espinola, RG., et al. 2003. J Thromb Haemost. 1: 843-8. PMID: 12871424
- E-selectin regulates gene expression in metastatic colorectal carcinoma cells and enhances HMGB1 release. | Aychek, T., et al. 2008. Int J Cancer. 123: 1741-50. PMID: 18324679
- Analysis of physiologic E-selectin-mediated leukocyte rolling on microvascular endothelium. | Wiese, G., et al. 2009. J Vis Exp.. PMID: 19229187
- Intranasal delivery of E-selectin reduces atherosclerosis in ApoE-/- mice. | Li, X., et al. 2011. PLoS One. 6: e20620. PMID: 21701687
- Combined Ibuprofen-Nanoconjugate Micelles with E-Selectin for Effective Sunitinib Anticancer Therapy. | Zeng, X., et al. 2022. Int J Nanomedicine. 17: 6031-6046. PMID: 36510619
- Phosphorylation of surface E-selectin and the effect of soluble ligand (sialyl Lewisx) on the half-life of E-selectin. | Smeets, EF., et al. 1993. Eur J Immunol. 23: 147-51. PMID: 7678223
- E-selectin in focal cerebral ischemia and reperfusion in the rat. | Zhang, RL., et al. 1996. J Cereb Blood Flow Metab. 16: 1126-36. PMID: 8898684
- Visualising E-selectin in the detection and evaluation of inflammatory bowel disease. | Bhatti, M., et al. 1998. Gut. 43: 40-7. PMID: 9771404
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
E-Selectin/CD62E/SELE Antibody (A-10) | sc-137203 | 200 µg/ml | $322.00 | |||
E-Selectin/CD62E/SELE Antibody (A-10): m-IgG Fc BP-HRP Bundle | sc-539957 | 200 µg Ab; 10 µg BP | $361.00 | |||
E-Selectin/CD62E/SELE Antibody (A-10): m-IgG1 BP-HRP Bundle | sc-541813 | 200 µg Ab; 20 µg BP | $361.00 |