E-Selectin/CD62E/SELE Antibody (2Q780): sc-71017

E-Selectin Antibody (2Q780) is a mouse monoclonal IgG1 antibody that detects E-Selectin in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). E-Selectin, also known as ELAM-1 or CD62E, is a crucial adhesion molecule expressed on the surface of endothelial cells, particularly during inflammatory responses. E-Selectin (2Q780) antibody helps identify this protein′s primary function in mediating leukocyte adhesion to vascular endothelium, facilitating migration to sites of inflammation. This process is vital for immune response, allowing immune cells to exit the bloodstream and reach tissues where needed to combat infection or injury. E-Selectin is upregulated in response to pro-inflammatory cytokines, making anti-E-Selectin antibody (2Q780) valuable for studying leukocyte recruitment during inflammatory processes. The interaction of E-Selectin with specific carbohydrates on leukocytes is essential for rolling and adhesion of these cells, a critical step in inflammatory response. E-Selectin monoclonal antibody (2Q780) enables researchers to gain insights into inflammation mechanisms and E-Selectin′s role in various pathological conditions, enhancing understanding of immune responses and potential therapeutic targets.

The preferred E-Selectin/CD62E/SELE antibody is E-Selectin/CD62E/SELE Antibody (D-7): sc-137054.