E. coli K99 Antibody (6911): sc-57716

E. coli K99 Antibody (6911) is a mouse monoclonal IgG1 kappa light chain antibody that detects the E. coli K99 protein of E. coli origin by enzyme-linked immunosorbent assay (ELISA). Anti-E. coli K99 antibody (6911) is available as the non-conjugated format. The K99 protein, a pilus antigen, is crucial for the adhesion of E. coli to the intestinal epithelium, facilitating colonization and infection in the small intestine. This interaction allows E. coli to establish itself in the host, leading to various infections such as urinary tract infections, meningitis, and septicemia. Understanding the role of K99 protein in bacterial adhesion not only sheds light on the pathogenic mechanisms of E. coli but also aids in the development of targeted therapies and vaccines. Escherichia coli, a member of the Enterobacteriaceae family, is a Gram-negative, rod-shaped bacterium commonly found in the lower intestines of mammals and serves as a model organism in microbiological research. E. coli′s ability to be genetically manipulated for the production of proteins and DNA makes this bacterium a valuable tool in biotechnology and industrial applications.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

E. coli K99 Antibody (6911) References:

1. Escherichia coli K1 internalization via caveolae requires caveolin-1 and protein kinase Calpha interaction in human brain microvascular endothelial cells.  |  Sukumaran, SK., et al. 2002. J Biol Chem. 277: 50716-24. PMID: 12386163
2. Escherichia coli K1 RS218 interacts with human brain microvascular endothelial cells via type 1 fimbria bacteria in the fimbriated state.  |  Teng, CH., et al. 2005. Infect Immun. 73: 2923-31. PMID: 15845498
3. Effect of the thyroid on faecal shedding of E. coli O157:H7 and Escherichia coli in naturally infected yearling beef cattle.  |  Schultz, CL., et al. 2005. J Appl Microbiol. 99: 1176-80. PMID: 16238748
4. Survival of antibiotic resistant and antibiotic sensitive strains of E. coli O157 and E. coli O26 in food matrices.  |  Duffy, G., et al. 2006. Int J Food Microbiol. 109: 179-86. PMID: 16504330
5. The influence of melatonin on growth of E. coli O157:H7 in pure culture and exogenous melatonin on faecal shedding of E. coli O157:H7 in experimentally infected wethers.  |  Schultz, CL., et al. 2006. Lett Appl Microbiol. 43: 105-10. PMID: 16834729
6. Effects of ompA deletion on expression of type 1 fimbriae in Escherichia coli K1 strain RS218 and on the association of E. coli with human brain microvascular endothelial cells.  |  Teng, CH., et al. 2006. Infect Immun. 74: 5609-16. PMID: 16988236
7. Enteropathogenic Escherichia coli disease: new developments and perspectives.  |  South, MA. 1971. J Pediatr. 79: 1-11. PMID: 4933215
8. Construction and characterization of a chimeric plasmid composed of DNA Pfrom Escherichia coli and Drosophila melanogaster.  |  Tanaka, T., et al. 1975. Biochemistry. 14: 2064-72. PMID: 807234
9. Neonatal early-onset Escherichia coli disease. The effect of intrapartum ampicillin.  |  Joseph, TA., et al. 1998. Arch Pediatr Adolesc Med. 152: 35-40. PMID: 9452705

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-E. coli K99 Antibody (6911) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

E. coli K99 Antibody (6911) Specifications

Alternate Product Name: E. coli K99

Product Clone Name: 6911

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: mouse IgG₁ κ kappa light chain

Amino Acids:

Epitope Target: E. coli K99

Epitope Species: E. coli

Product Reactivity/Detection: K99

Species Reactivity/Detection: E. coli

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for E. coli K99 Antibody (6911): N/A