DSC3 Antibody (93-71): sc-81806
- DSC3 Antibody (93-71) is a mouse monoclonal IgG2b κ, cited in 3 publications, provided at 100 µg/ml
- raised against recombinant DSC3 of human origin
- recommended for detection of DSC3A and DSC3B of human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for DSC3 Antibody (93-71). This work is in progress.
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DSC3 Antibody (93-71) is a mouse monoclonal IgG2b antibody that detects desmocollin DSC3 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DSC3 is a type I membrane protein that plays a crucial role in maintaining the structural integrity and adhesion of epithelial tissues, particularly in the epidermis and various stratified epithelia, including the cervix, tongue, and esophagus. DSC3 presence in desmosomes facilitates strong intercellular adhesion, which is essential for tissue resilience against mechanical stress and contributes to the overall barrier function of the skin. DSC3 is expressed in all living layers of the epidermis, as well as in glandular ducts and the outer root sheath of hair follicles, highlighting DSC3′s importance in both epidermal differentiation and cellular organization. DSC3 undergoes alternative splicing, resulting in two isoforms, DSC3A and DSC3B, which differ in their carboxy termini and may influence the adhesive properties of cells expressing these variants. By mediating differential adhesiveness, DSC3 plays a significant role in epidermal cell positioning, thereby impacting tissue architecture and function. Anti-DSC3 antibody (93-71) serves as an invaluable tool for researchers studying the dynamics of desmosomal adhesion and the molecular mechanisms underlying epithelial integrity.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DSC3 Antibody (93-71) | sc-81806 | 100 µg/ml | $333.00 |