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DP-2 Antibody (G-12) is a mouse monoclonal IgG2b antibody that detects DP-2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DP-2, a member of the E2F family of transcription factors, plays a crucial role in regulating the cell cycle, particularly during the transition from G1 phase to S phase. DP-2 regulation is vital for proper cell proliferation and differentiation, as dysregulation can lead to uncontrolled cell growth and contribute to tumorigenesis. DP-2 interacts with other proteins, including DP-1, to form an active E2F transcriptional regulatory complex, which is essential for transcriptional activation of genes involved in cell cycle progression. DP-2 forms heterodimers with DP-1 to enhance transcriptional activity, thereby influencing expression of genes critical for cell cycle control. Understanding DP-2 function and interactions is important for elucidating mechanisms underlying cell proliferation and potential implications in cancer biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DP-2 Antibody (G-12) | sc-6849 | 200 µg/ml | $322.00 | |||
DP-2 Antibody (G-12) X | sc-6849 X | 200 µg/0.1 ml | $322.00 |