Dopamine Antibody (1.B.639): sc-70988
- Dopamine Antibody (1.B.639) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against dopamine conjugated wtih BSA
- recommended for detection of catecholamine of mouse, rat and human origin by IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Dopamine Antibody (1.B.639). This work is in progress.
QUICK LINKS
SEE ALSO...
Dopamine Antibody (1.B.639) is a mouse monoclonal IgG1 antibody that recognizes dopamine in mouse, rat, and human samples through immunofluorescence (IF) applications. Dopamine is a crucial catecholamine neurotransmitter primarily expressed in the brain, where anti-dopamine antibody (1.B.639) helps researchers study its vital role in activating dopamine receptors and modulating various neurological functions. Dopamine′s significance extends beyond neurotransmission, acting as a neurohormone released by the hypothalamus to influence prolactin release from the anterior pituitary gland. The structure of dopamine, with its catechol group and amine side chain, enables receptor interaction and blood-brain barrier crossing, which is critical for physiological effects. Dysregulation of dopamine levels is implicated in several neuropsychiatric disorders, including schizophrenia and Parkinson′s disease, making dopamine monoclonal antibody (1.B.639) an invaluable tool for studying these complex pathways and dopamine′s role in various biological processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Dopamine Antibody (1.B.639) References:
- Dopamine receptor localization in the mammalian retina. | Nguyen-Legros, J., et al. 1999. Mol Neurobiol. 19: 181-204. PMID: 10495103
- Dopamine receptor homooligomers and heterooligomers in schizophrenia. | Perreault, ML., et al. 2011. CNS Neurosci Ther. 17: 52-7. PMID: 21199449
- Dopamine-based reward circuitry responsivity, genetics, and overeating. | Stice, E., et al. 2011. Curr Top Behav Neurosci. 6: 81-93. PMID: 21243471
- Dopamine in anorexia nervosa: a systematic review. | Kontis, D. and Theochari, E. 2012. Behav Pharmacol. 23: 496-515. PMID: 22854306
- Are dopamine D2 receptors out of control in psychosis? | Seeman, P. 2013. Prog Neuropsychopharmacol Biol Psychiatry. 46: 146-52. PMID: 23880595
- Dopamine receptor 3: A mystery at the heart of cardiac fibrosis. | Byrne, SE., et al. 2022. Life Sci. 308: 120918. PMID: 36041503
- Role of Dopamine in the Heart in Health and Disease. | Neumann, J., et al. 2023. Int J Mol Sci. 24: PMID: 36902474
- Dopamine action and metabolism in the kidney. | Aperia, A. 1994. Curr Opin Nephrol Hypertens. 3: 39-45. PMID: 7850410
- Dopamine receptor pharmacology. | Seeman, P. and Van Tol, HH. 1993. Curr Opin Neurol Neurosurg. 6: 602-8. PMID: 8104554
- Dopamine D2 and D4 receptor ligands: relation to antipsychotic action. | Wilson, JM., et al. 1998. Eur J Pharmacol. 351: 273-86. PMID: 9721018
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dopamine Antibody (1.B.639) | sc-70988 | 100 µg/ml | $322.00 |