The chemical class known as Dopamine Inhibitors embodies a diverse array of organic compounds that intricately modulate the intricate signaling pathways involving the neurotransmitter dopamine within the brain. These inhibitors exert their effects through various mechanisms, finely tuning the delicate balance of dopamine levels by targeting multiple stages of dopamine's journey. Their influence spans from the biosynthesis of dopamine to its release, reuptake, and interactions with specific receptors. At the heart of their action lies a precise interplay with the machinery of dopamine regulation. Some inhibitors impede the packaging and storage of dopamine into synaptic vesicles, curtailing its subsequent release upon neuronal stimulation. Others interact with dopamine receptors, blocking their activation and altering the downstream signaling cascades. Additionally, certain inhibitors thwart the reuptake of dopamine, extending its presence within synapses and amplifying its signaling impact.
The evolution of dopamine inhibitors reflects the symbiotic relationship between chemical design and the complexities of neural communication. Researchers have skillfully tailored these compounds, crafting molecular structures that can interact with specific targets within the dopamine signaling cascade. These interactions manifest as a harmonious dance between inhibitor and dopamine-related components, choreographed with precision at the molecular level. The exploration of dopamine inhibitors delves beyond the boundaries of the chemical realm, unveiling an intricate symphony of molecular events within the brain. By deciphering the minutiae of their interactions with dopamine-related processes, scientists illuminate the neural pathways that underlie diverse physiological functions.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Reserpine | 50-55-5 | sc-203370 sc-203370A | 1 g 5 g | $134.00 $406.00 | 1 | |
Reserpine inhibits the vesicular monoamine transporter (VMAT), leading to decreased storage of dopamine in vesicles and subsequent reduction in dopamine release. | ||||||
Tetrabenazine | 58-46-8 | sc-204338 sc-204338A | 10 mg 50 mg | $165.00 $707.00 | ||
Tetrabenazine depletes dopamine by inhibiting VMAT, thereby curbing dopamine storage and release. | ||||||
Haloperidol | 52-86-8 | sc-507512 | 5 g | $190.00 | ||
Haloperidol exerts its effect by blocking dopamine D2 receptors, which helps manage symptoms of psychosis but may lead to reduced dopamine signaling in certain brain regions. | ||||||
Metoclopramide | 364-62-5 | sc-358363 | 100 g | $465.00 | 1 | |
Metoclopramide is an agent in research that inhibits dopamine D2 receptors. It is often prescribed for gastrointestinal disorders and nausea but can influence central dopamine pathways. | ||||||
Pimozide | 2062-78-4 | sc-203662 | 100 mg | $102.00 | 3 | |
Pimozide i targets dopamine D2 receptors. Its use helps manage symptoms of certain psychiatric disorders, and its mechanism involves attenuating dopamine signaling. | ||||||
Aripiprazole | 129722-12-9 | sc-207300 sc-207300A sc-207300B | 100 mg 1 g 5 g | $175.00 $208.00 $1017.00 | 3 | |
Aripiprazole functions as a partial agonist at dopamine D2 receptors. It modulates dopamine signaling by acting as both an agonist and antagonist, depending on the context. | ||||||
Risperidone | 106266-06-2 | sc-204881 sc-204881A sc-204881B sc-204881C | 10 mg 50 mg 1 g 5 g | $171.00 $705.00 $1000.00 $2000.00 | 1 | |
Risperidone antagonizes dopamine D2 receptors, contributing to its therapeutic effects in impacting schizophrenia and related conditions. | ||||||
(RS)-(±)-Sulpiride | 15676-16-1 | sc-205494 | 100 mg | $69.00 | ||
Sulpiride primarily targets dopamine D2 receptors, thus exerting a regulatory effect on dopamine neurotransmission. | ||||||
Domperidone | 57808-66-9 | sc-203032 sc-203032A | 50 mg 250 mg | $60.00 $281.00 | 2 | |
Domperidone inhibits dopamine D2 receptors. Its primary mechanism is unrelated to dopamine, but its action on these receptors can have secondary effects. |