Dobutamine Hydrochloride CAS: 49745-95-1
MF: C18H23NO3•HCl
MW: 337.85
A dopamine derived β1-AR agonist.

Dobutamine Hydrochloride (CAS 49745-95-1)

Dobutamine Hydrochloride | CAS 49745-95-1 is rated 5.0 out of 5 by 1.
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Alternate Names: Dobutrex
Application: Dobutamine Hydrochloride is a dopamine derived β1-AR agonist
CAS Number: 49745-95-1
Purity: ≥99%
Molecular Weight: 337.85
Molecular Formula: C18H23NO3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Dobutamine Hydrochloride is a derivative of dopamine and is used as a β1-adrenergic receptor (β1-AR) agonist. Also shows potential action with β2-AR and α1-AR targets as well. Due to its ability to directly stimulate the sympathetic nervous system, Dobutamine Hydrochloride has been utilized as a sympathomimetic drug.


References

1. Weber, R. and Tuttle, R. 1977. Rnai: Pharmacological and Biochemical Properties of Drug Substances vol. 1. Goldberg, M.E. ed. Washington, D.C. Am. Pharm. Assoc. Washington, D.C. pp. 109-124

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (10 mg/ml, with gentle heating), ethanol (20 mg/ml, with gentle heating), methanol, pyridine, and DMSO (100 mM).
Storage :
Store at room temperature
Melting Point :
188-189° C
Boiling Point :
527.7° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.61 (Predicted)
IC50 :
Plasmodium falciparum: IC50 = 10 µM
pK Values :
pKa: 9.45
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
CZ9001000
PubChem CID :
65324
Merck Index :
14: 3395
MDL Number :
MFCD00153795
EC Number :
256-464-1
Beilstein Registry :
6023420
SMILES :
CC(CCC1=CC=C(C=C1)O)NCCC2=CC(=C(C=C2)O)O.Cl

Download SDS (MSDS)

Certificate of Analysis

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Dobutamine Hydrochloride (CAS 49745-95-1)  Product Citations

See how others have used Dobutamine Hydrochloride (CAS 49745-95-1). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 24828496  van der Hagen, EA. et al. 2014. J. Biol. Chem. 289: 18489-96.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Mert Mert, et al. (PubMed ID 26398398) found that dobutamine can ameliorate oxidative stress, thus be beneficial in diabetes induced neuropathic pain in diabetic rats. -SCBT Publication Review
Date published: 2015-02-24
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