Dieser polyklonale Antikörper wird nicht mehr hergestellt. Wir empfehlen Ihnen unseren Dnmt3L (A-4) monoklonalen Antikörper (Beispielsdaten werden angezeigt).
Dnmt3L Antikörper (N-14): sc-10239
- Dnmt3L Antikörper N-14 ist ein polyklonales IgG aus der Ziege in einer Menge von 200 µg/ml
- das Epitop liegt in der Nähe des N-terminus von Dnmt3L aus der Spezies human
- Nicht länger erhältlicher polyklonaler Antikörper
Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines, thereby repressing expression of the target gene. Dnmt3L (DNA (cytosine-5)-methyltransferase 3-like) is a 387 amino acid protein that contains one ADD-type zinc finger and is a member of the Dnmt family. Localized to the nucleus and expressed at lows levels in thymus, testis and ovary, Dnmt3L does not exhibit DNA methyltransferase activity, but is able to stimulate de novo methylation by Dnmt3 and is thought to play a key role in the establishment of genomic imprints. Additionally, Dnmt3L interacts with histone deacetylase 1 (HDAC1) and, through this interaction, mediates transcriptional repression. Multiple isoforms of Dnmt3L exist due to alternative splicing events.
Bestellinformation
Dnmt3L (A-4): sc-393603 [ Empfohlener monoklonaler Ersatz für Dnmt3L (N-14) ]
| Produkt | Katalog # | EINHEIT | Preis | ANZAHL | Favoriten | |
Dnmt3L Antikörper (A-4) | sc-393603 | 200 µg/ml | $316.00 | |||
Dnmt3L (A-4): m-IgG Fc BP-HRP Bundle | sc-526259 | 200 µg Ab; 10 µg BP | $354.00 | |||
Dnmt3L Antikörper (A-4) AC | sc-393603 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Dnmt3L Antikörper (A-4) HRP | sc-393603 HRP | 200 µg/ml | $316.00 | |||
Dnmt3L Antikörper (A-4) FITC | sc-393603 FITC | 200 µg/ml | $330.00 | |||
Dnmt3L Antikörper (A-4) PE | sc-393603 PE | 200 µg/ml | $343.00 | |||
Dnmt3L Antikörper (A-4) Alexa Fluor® 488 | sc-393603 AF488 | 200 µg/ml | $357.00 | |||
Dnmt3L Antikörper (A-4) Alexa Fluor® 546 | sc-393603 AF546 | 200 µg/ml | $357.00 | |||
Dnmt3L Antikörper (A-4) Alexa Fluor® 594 | sc-393603 AF594 | 200 µg/ml | $357.00 | |||
Dnmt3L Antikörper (A-4) Alexa Fluor® 647 | sc-393603 AF647 | 200 µg/ml | $357.00 | |||
Dnmt3L Antikörper (A-4) Alexa Fluor® 680 | sc-393603 AF680 | 200 µg/ml | $357.00 | |||
Dnmt3L Antikörper (A-4) Alexa Fluor® 790 | sc-393603 AF790 | 200 µg/ml | $357.00 |