DNALI1 Antibody (G-12): sc-514831
- DNALI1 Antibody (G-12) is a mouse monoclonal IgG2b κ DNALI1 antibody provided at 200 µg/ml
- raised against amino acids 23-156 mapping within an internal region of DNALI1 of human origin
- DNALI1 Antibody (G-12) is recommended for detection of DNALI1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-DNALI1 Antibody (G-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for DNALI1 Antibody (G-12) for WB applications. These reagents are now offered in bundles with DNALI1 Antibody (G-12) (see ordering information below).
QUICK LINKS
DNALI1 Antibody (G-12) is a mouse monoclonal IgG2b kappa light chain antibody that detects DNALI1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-DNALI1 antibody (G-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. DNALI1, also known as dynein, axonemal, light intermediate chain 1, plays a crucial role in flagellar motility, which is essential for sperm movement and proper functioning of cilia in various cell types. This 258 amino acid protein is a member of the inner dynein arm light chain family and is predominantly expressed in testis, highlighting its importance in reproductive biology. Proper functioning of DNALI1 is vital, as mutations or deficiencies can lead to immotile cilia syndrome, a condition affecting ciliary movement that can result in respiratory issues and infertility. DNALI1 (G-12) antibody enables researchers to gain valuable insights into mechanisms of ciliary movement and underlying causes of related disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
DNALI1 Antibody (G-12) References:
- Dynein light chain binding to a 3'-untranslated sequence mediates parathyroid hormone mRNA association with microtubules. | Epstein, E., et al. 2000. J Clin Invest. 105: 505-12. PMID: 10683380
- ADP-dependent microtubule translocation by flagellar inner-arm dyneins. | Yagi, T. 2000. Cell Struct Funct. 25: 263-7. PMID: 11129796
- A novel transforming growth factor-beta receptor-interacting protein that is also a light chain of the motor protein dynein. | Tang, Q., et al. 2002. Mol Biol Cell. 13: 4484-96. PMID: 12475967
- Backbone dynamics of dynein light chains. | Wu, H. and King, SM. 2003. Cell Motil Cytoskeleton. 54: 267-73. PMID: 12601689
- Recruitment of dynein to the Jurkat immunological synapse. | Combs, J., et al. 2006. Proc Natl Acad Sci U S A. 103: 14883-8. PMID: 16990435
- Multiple mouse chromosomal loci for dynein-based motility. | Vaughan, KT., et al. 1996. Genomics. 36: 29-38. PMID: 8812413
- Complementary deoxyribonucleic acid cloning and characterization of a putative human axonemal dynein light chain gene. | Kastury, K., et al. 1997. J Clin Endocrinol Metab. 82: 3047-53. PMID: 9284741
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DNALI1 Antibody (G-12) | sc-514831 | 200 µg/ml | $316.00 | |||
DNALI1 Antibody (G-12): m-IgGκ BP-HRP Bundle | sc-524858 | 200 µg Ab, 40 µg BP | $354.00 | |||
DNALI1 Antibody (G-12): m-IgG2b BP-HRP Bundle | sc-549191 | 200 µg Ab; 10 µg BP | $354.00 | |||
DNALI1 Antibody (G-12) AC | sc-514831 AC | 500 µg/ml, 25% agarose | $416.00 | |||
DNALI1 Antibody (G-12) HRP | sc-514831 HRP | 200 µg/ml | $316.00 | |||
DNALI1 Antibody (G-12) FITC | sc-514831 FITC | 200 µg/ml | $330.00 | |||
DNALI1 Antibody (G-12) PE | sc-514831 PE | 200 µg/ml | $343.00 | |||
DNALI1 Antibody (G-12) Alexa Fluor® 488 | sc-514831 AF488 | 200 µg/ml | $357.00 | |||
DNALI1 Antibody (G-12) Alexa Fluor® 546 | sc-514831 AF546 | 200 µg/ml | $357.00 | |||
DNALI1 Antibody (G-12) Alexa Fluor® 594 | sc-514831 AF594 | 200 µg/ml | $357.00 | |||
DNALI1 Antibody (G-12) Alexa Fluor® 647 | sc-514831 AF647 | 200 µg/ml | $357.00 | |||
DNALI1 Antibody (G-12) Alexa Fluor® 680 | sc-514831 AF680 | 200 µg/ml | $357.00 | |||
DNALI1 Antibody (G-12) Alexa Fluor® 790 | sc-514831 AF790 | 200 µg/ml | $357.00 |