DnaJC1 Antibody (D-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects DnaJC1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-DnaJC1 antibody (D-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. DnaJC1, also known as DnaJ homolog subfamily C member 1, plays a vital role in cellular protein homeostasis by functioning as a molecular chaperone. DnaJC1 is primarily located in the endoplasmic reticulum, nucleus, and microsome, where DnaJC1 assists in the proper folding of nascent polypeptides and the refolding of misfolded proteins. DnaJC1′s presence in these cellular compartments is crucial, as DnaJC1 helps maintain protein quality control, which is essential for cellular function and survival. DnaJC1 contains a J domain that interacts with HSP 70, facilitating ATP hydrolysis, and two SANT domains that bind to GRP 78 and AACT, respectively. Additionally, through a cytosolic domain, DnaJC1 interacts with ribosomes, suggesting a role in modulating protein synthesis. DnaJC1 gene is located on human chromosome 10p12.31 and mouse chromosome 2 A3, highlighting evolutionary conservation and importance across species.
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Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DnaJC1 Antibody (D-10) | sc-514244 | 200 µg/ml | $316.00 | |||
DnaJC1 Antibody (D-10): m-IgG Fc BP-HRP Bundle | sc-527874 | 200 µg Ab; 10 µg BP | $354.00 | |||
DnaJC1 Antibody (D-10): m-IgG1 BP-HRP Bundle | sc-533247 | 200 µg Ab; 20 µg BP | $354.00 | |||
DnaJC1 Antibody (D-10) X | sc-514244 X | 200 µg/0.1 ml | $316.00 | |||
DnaJC1 Antibody (D-10) AC | sc-514244 AC | 500 µg/ml, 25% agarose | $416.00 | |||
DnaJC1 Antibody (D-10) HRP | sc-514244 HRP | 200 µg/ml | $316.00 | |||
DnaJC1 Antibody (D-10) FITC | sc-514244 FITC | 200 µg/ml | $330.00 | |||
DnaJC1 Antibody (D-10) PE | sc-514244 PE | 200 µg/ml | $343.00 | |||
DnaJC1 Antibody (D-10) Alexa Fluor® 488 | sc-514244 AF488 | 200 µg/ml | $357.00 | |||
DnaJC1 Antibody (D-10) Alexa Fluor® 546 | sc-514244 AF546 | 200 µg/ml | $357.00 | |||
DnaJC1 Antibody (D-10) Alexa Fluor® 594 | sc-514244 AF594 | 200 µg/ml | $357.00 | |||
DnaJC1 Antibody (D-10) Alexa Fluor® 647 | sc-514244 AF647 | 200 µg/ml | $357.00 | |||
DnaJC1 Antibody (D-10) Alexa Fluor® 680 | sc-514244 AF680 | 200 µg/ml | $357.00 | |||
DnaJC1 Antibody (D-10) Alexa Fluor® 790 | sc-514244 AF790 | 200 µg/ml | $357.00 |