Dlx-2 Antibody (B-5): sc-393879
- Dlx-2 Antibody (B-5) is a mouse monoclonal IgG2a κ Dlx-2 antibody, cited in 8 publications, provided at 200 µg/ml
- raised against amino acids 211-250 mapping within an internal region of Dlx-2 of human origin
- Dlx-2 Antibody (B-5) is recommended for detection of Dlx-2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Dlx-2 Antibody (B-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-393879 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for Dlx-2 Antibody (B-5) for WB applications. These reagents are now offered in bundles with Dlx-2 Antibody (B-5) (see ordering information below).
Dlx-2 Antibody (B-5) is a mouse monoclonal IgG2a kappa light chain antibody that detects Dlx-2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Dlx-2 (B-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Dlx-2 protein plays a crucial role in the development of the craniofacial skeleton and is involved in the differentiation of structures within and between teeth, making Dlx-2 essential for proper tissue morphogenesis. Dlx-2 is part of a highly conserved family of homeobox genes, which are critical for regulating gene expression during embryonic development. Dlx-2 genes are expressed in specific patterns in various tissues, including the craniofacial primordia and the developing brain, influencing the formation and organization of these structures. Dlx-2′s ability to activate transcription and predominant localization in the nucleus underscore Dlx-2′s importance in developmental processes, as Dlx-2 orchestrates the intricate signaling pathways necessary for the proper formation of craniofacial and dental structures.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Dlx-2 Antibody (B-5) References:
- Expression of DLX5 during human embryonic craniofacial development. | Davideau, JL., et al. 1999. Mech Dev. 81: 183-6. PMID: 10330497
- Dlx5 regulates regional development of the branchial arches and sensory capsules. | Depew, MJ., et al. 1999. Development. 126: 3831-46. PMID: 10433912
- DLX-1, DLX-2, and DLX-5 expression define distinct stages of basal forebrain differentiation. | Eisenstat, DD., et al. 1999. J Comp Neurol. 414: 217-37. PMID: 10516593
- Roles for Msx and Dlx homeoproteins in vertebrate development. | Bendall, AJ. and Abate-Shen, C. 2000. Gene. 247: 17-31. PMID: 10773441
- Multiple functions of Dlx genes. | Merlo, GR., et al. 2000. Int J Dev Biol. 44: 619-26. PMID: 11061425
- Dlx-1 and Dlx-2 expression in the adult mouse brain: relationship to dopaminergic phenotypic regulation. | Saino-Saito, S., et al. 2003. J Comp Neurol. 461: 18-30. PMID: 12722102
- A partial cDNA sequence of the Dlx-2 cDNA. | Porteus, MH., et al. 1992. Neuron. 9: 187. PMID: 1632970
- Dlx-2 and glutaminase upregulate epithelial-mesenchymal transition and glycolytic switch. | Lee, SY., et al. 2016. Oncotarget. 7: 7925-39. PMID: 26771232
- Reactive oxygen species induce epithelial‑mesenchymal transition, glycolytic switch, and mitochondrial repression through the Dlx‑2/Snail signaling pathways in MCF‑7 cells. | Lee, SY., et al. 2019. Mol Med Rep. 20: 2339-2346. PMID: 31322179
- Dlx and other homeobox genes in the morphological development of the dentition. | Weiss, KM., et al. 1995. Connect Tissue Res. 32: 35-40. PMID: 7554933
- Regionalization of the developing forebrain: a comparison of FORSE-1, Dlx-2, and BF-1. | Tole, S. and Patterson, PH. 1995. J Neurosci. 15: 970-80. PMID: 7869122
- The human brain homeogene, DLX-2: cDNA sequence and alignment with the murine homologue. | Selski, DJ., et al. 1993. Gene. 132: 301-3. PMID: 7901126
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dlx-2 Antibody (B-5) | sc-393879 | 200 µg/ml | $322.00 | |||
Dlx-2 Antibody (B-5): m-IgG Fc BP-HRP Bundle | sc-526271 | 200 µg Ab; 10 µg BP | $361.00 | |||
Dlx-2 Antibody (B-5): m-IgG2a BP-HRP Bundle | sc-546552 | 200 µg Ab; 10 µg BP | $361.00 | |||
Dlx-2 Antibody (B-5) X | sc-393879 X | 200 µg/0.1 ml | $322.00 | |||
Dlx-2 Antibody (B-5) AC | sc-393879 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Dlx-2 Antibody (B-5) HRP | sc-393879 HRP | 200 µg/ml | $322.00 | |||
Dlx-2 Antibody (B-5) FITC | sc-393879 FITC | 200 µg/ml | $336.00 | |||
Dlx-2 Antibody (B-5) PE | sc-393879 PE | 200 µg/ml | $349.00 | |||
Dlx-2 Antibody (B-5) Alexa Fluor® 488 | sc-393879 AF488 | 200 µg/ml | $364.00 | |||
Dlx-2 Antibody (B-5) Alexa Fluor® 546 | sc-393879 AF546 | 200 µg/ml | $364.00 | |||
Dlx-2 Antibody (B-5) Alexa Fluor® 594 | sc-393879 AF594 | 200 µg/ml | $364.00 | |||
Dlx-2 Antibody (B-5) Alexa Fluor® 647 | sc-393879 AF647 | 200 µg/ml | $364.00 | |||
Dlx-2 Antibody (B-5) Alexa Fluor® 680 | sc-393879 AF680 | 200 µg/ml | $364.00 | |||
Dlx-2 Antibody (B-5) Alexa Fluor® 790 | sc-393879 AF790 | 200 µg/ml | $364.00 |