DECR1 Antibody (30-P): sc-130369
- DECR1 Antibody (30-P) is a mouse monoclonal IgG2a κ provided at 100 µg/ml
- raised against recombinant DECR1 of human origin
- recommended for detection of DECR1 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for DECR1 Antibody (30-P). This work is in progress.
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DECR1 Antibody (30-P) is a mouse monoclonal IgG2a antibody that detects DECR1 in human samples through western blotting (WB) and immunoprecipitation (IP) applications. DECR1, or 2,4-dienoyl-CoA reductase, mitochondrial, is a crucial 335 amino acid mitochondrial protein that plays a significant role in the metabolism of unsaturated fatty acids. DECR1 is primarily located in the mitochondria, where DECR1 exists as a homotetramer and belongs to the family of short-chain dehydrogenases/reductases. The localization of DECR1 in the mitochondria is vital as mitochondria are the site of energy production and fatty acid metabolism, making DECR1 essential for maintaining cellular energy homeostasis. DECR1 functions as an auxiliary enzyme in the beta-oxidation pathway, specifically catalyzing the reduction of 2,4-dienoyl-CoA to trans-3-enoyl-CoA using NADP+, which is then utilized as an intermediate in the Krebs cycle. Furthermore, DECR1 is believed to have tumor suppressor properties, potentially downregulating the expression of Neu and inhibiting tumorigenesis. anti-DECR1 antibody (30-P) is an invaluable tool for researchers studying fatty acid metabolism and its implications in various diseases, including cancer.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DECR1 Antibody (30-P) | sc-130369 | 100 µg/ml | $333.00 |