DDX29 Antibody (2269C1): sc-81080
- DDX29 Antibody (2269C1) is a mouse monoclonal IgG1, cited in 2 publications, provided at 100 µg/ml
- raised against a recombinant protein corresponding to a region near the N-terminus of DDX29 of human origin
- recommended for detection of DDX29 of human origin by WB, IP and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for DDX29 Antibody (2269C1). This work is in progress.
DDX29 Antibody (2269C1) is a mouse monoclonal IgG1 antibody that detects DDX29 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). DDX29 is a 1,369 amino acid protein encoded by the human gene DDX29 and is a member of the DEAD box helicase family, specifically the DEAH subfamily, characterized by its helicase ATP-binding domain and helicase C-terminal domain. DDX29 is predominantly located in the nucleus and plays a crucial role as an ATP-dependent RNA helicase, which is essential for various RNA-related biological processes, including transcription, splicing, and translation. DDX29′s ability to modulate RNA structure through the energy derived from nucleoside triphosphate hydrolysis is vital for maintaining proper cellular function and gene expression. Furthermore, DDX29 interacts with several specific proteins involved in RNA metabolism, enhancing its importance in the regulation of RNA dynamics within the cell. Anti-DDX29 antibody (2269C1) is an invaluable tool for researchers studying RNA processing and the intricate mechanisms of gene regulation in human cells.
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DDX29 Antibody (2269C1) References:
- Overexpression of a DEAD box/RNA helicase protein, rck/p54, in human hepatocytes from patients with hepatitis C virus-related chronic hepatitis and its implication in hepatocellular carcinogenesis. | Miyaji, K., et al. 2003. J Viral Hepat. 10: 241-8. PMID: 12823589
- mRNA export: threading the needle. | Gaouar, O. and Germain, H. 2013. Front Plant Sci. 4: 59. PMID: 23526740
- DEAD-box helicase proteins disrupt RNA tertiary structure through helix capture. | Pan, C., et al. 2014. PLoS Biol. 12: e1001981. PMID: 25350280
- High-Throughput Screening to Identify Inhibitors of DEAD Box Helicase DDX41. | Yoneyama-Hirozane, M., et al. 2017. SLAS Discov. 22: 1084-1092. PMID: 28426938
- DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA. | Gao, J., et al. 2019. Chem Commun (Camb). 55: 4467-4470. PMID: 30855040
- Genome-wide identification, characterisation and expression profile analysis of DEAD-box family genes in sweet potato wild ancestor Ipomoea trifida under abiotic stresses. | Wan, R., et al. 2020. Genes Genomics. 42: 325-335. PMID: 31894476
- Gametophyte-specific DEAD-box RNA helicase 29 is required for functional maturation of male and female gametophytes in Arabidopsis. | Chen, D., et al. 2020. J Exp Bot. 71: 4083-4092. PMID: 32280991
- The DEAD-box helicase Hlc regulates basal transcription and chromatin opening of stress-responsive genes. | Jia, R., et al. 2022. Nucleic Acids Res. 50: 9175-9189. PMID: 35950495
- A DEAD-box helicase drives the partitioning of a pro-differentiation NAB protein into nuclear foci. | Doi, A., et al. 2023. Nat Commun. 14: 6593. PMID: 37852948
- DEAD-box helicase family proteins: emerging targets in digestive system cancers and advances in targeted drug development. | Ma, X., et al. 2024. J Transl Med. 22: 1120. PMID: 39707322
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DDX29 Antibody (2269C1) | sc-81080 | 100 µg/ml | $339.00 |