Anti-DcR1 Antibody (C-6) is a mouse monoclonal IgG2a (kappa light chain) DcR1 antibody provided at 200 µg/ml
raised against amino acids 131-259 mapping at the C-terminus of DcR1 of human origin
DcR1 Antibody (C-6) is recommended for detection of precursor and mature DcR1 of human origin by WB, IP, IF and ELISA
Anti-DcR1 Antibody (C-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of DcR1 (C-6): sc-365279.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
DcR1 Antibody (C-6) is a high quality monoclonal DcR1 antibody (also designated DcR1 antibody) suitable for the detection of the DcR1 protein of human origin. DcR1 Antibody (C-6) is available as both the non-conjugated anti-DcR1 antibody form, as well as multiple conjugated forms of anti-DcR1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF receptor superfamily which includes FAS antigen and CD40. TNF-R1 contains a cytoplasmic motif, termed the "death domain," that has been found to be necessary for the transduction of the apoptotic signal. The death domain is also found in several other receptors, including FAS, DR2 (or TRUNDD), DR3 (death receptor 3), DR4, DR5 and DR6. TRUNDD, DR4 and DR5 are receptors for the apoptosis-inducing cytokine TRAIL. Non-death domain-containing receptors, designated decoy receptor 1 (DcR1) or TRID, DcR2 and DcR3, associate with specific ligands and may play a role in cellular resistance to apoptotic stimuli.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
What is the recommended fixation method for immunofluorescence staining with DcR1 (C-6): sc-365279 monoclonal antibody?
Asked by: DefinitelyNotMatt
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here:
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn