DC-SIGN/DC-SIGNR Antibody (14E3G7): sc-53965
- DC-SIGN/DC-SIGNR Antibody (14E3G7) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- raised against DC-SIGN of human origin
- recommended for detection of DC-SIGN and DC-SIGNR of human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for DC-SIGN/DC-SIGNR Antibody (14E3G7). This work is in progress.
DC-SIGN/DC-SIGNR Antibody (14E3G7) is a mouse monoclonal IgG2b antibody that detects DC-SIGN/DC-SIGNR in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). DC-SIGN, also known as CD209, is a type II membrane protein predominantly expressed on dendritic cells, which play a crucial role in the immune response by presenting antigens to T cells. DC-SIGN/DC-SIGNR (14E3G7) antibody recognizes proteins that facilitate the capture and transmission of pathogens, including HIV-1, to T cells, thereby enhancing the immune system′s ability to respond to infections. This interaction is vital for initiating immune responses, particularly in the context of viral infections, as DC-SIGN allows dendritic cells to migrate to lymphoid tissues where they can effectively activate T cells. Additionally, DC-SIGNR, or CD209L, shares a significant structural similarity with DC-SIGN and is expressed on sinusoidal endothelial cells, where DC-SIGNR binds to the E2 glycoproteins of the hepatitis C virus, further underscoring the importance of these proteins in immune surveillance and pathogen recognition. Anti-DC-SIGN/DC-SIGNR antibody (14E3G7) serves as an essential tool for researchers studying immune responses and the mechanisms of viral infections, providing insights into the complex interactions between dendritic cells and pathogens.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DC-SIGN/DC-SIGNR Antibody (14E3G7) | sc-53965 | 200 µg/ml | $316.00 |