Daxx Antibody (DAXX-01): sc-51586

Daxx Antibody (DAXX-01) is a mouse monoclonal IgG1 antibody that detects Daxx in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Daxx is a multifunctional protein that plays a crucial role in the regulation of apoptosis, particularly in the context of the FAS signaling pathway. Daxx (DAXX-01) antibody targets proteins primarily located in the nucleus and cytoplasm of cells, where Daxx acts as a scaffold for various signaling molecules, thereby influencing cellular responses to stress and death signals. The localization of Daxx is significant because Daxx allows for the integration of multiple signaling pathways, including those involved in apoptosis and transcriptional regulation. Notably, Daxx interacts with several key proteins, including the death domain of FAS, which is essential for the initiation of apoptosis. This interaction highlights Daxx′s role as a mediator in the FAS pathway, linking extracellular death signals to intracellular apoptotic machinery. Furthermore, Daxx′s ability to modulate the activity of Jun N-terminal kinase (JNK) underscores its importance in cellular stress responses and the maintenance of tissue homeostasis. Anti-Daxx antibody (DAXX-01) serves as an invaluable tool for researchers studying apoptosis and related signaling pathways, providing insights into the complex mechanisms that govern cell fate decisions.

The preferred Daxx antibody is Daxx Antibody (H-7): sc-8043.