Molecular structure of D-Alanine, CAS Number: 338-69-2
D-Alanine (CAS 338-69-2)
Alternate Names:
(R)-2-Aminopropionic acid
Application:
D-Alanine is a weak inhibitory glycine receptor agonist
CAS Number:
338-69-2
Molecular Weight:
89.09
Molecular Formula:
C3H7NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
D-Alanine is a weak inhibitory glycine receptor agonist.
D-Alanine (CAS 338-69-2) References
- Roles of Mycobacterium smegmatis D-alanine:D-alanine ligase and D-alanine racemase in the mechanisms of action of and resistance to the peptidoglycan inhibitor D-cycloserine. | Feng, Z. and Barletta, RG. 2003. Antimicrob Agents Chemother. 47: 283-91. PMID: 12499203
- Sequence of the vanC gene of Enterococcus gallinarum BM4174 encoding a D-alanine:D-alanine ligase-related protein necessary for vancomycin resistance. | Dutka-Malen, S., et al. 1992. Gene. 112: 53-8. PMID: 1551598
- Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies. | Liu, S., et al. 2006. Proc Natl Acad Sci U S A. 103: 15178-83. PMID: 17015835
- The alanine racemase of Mycobacterium smegmatis is essential for growth in the absence of D-alanine. | Milligan, DL., et al. 2007. J Bacteriol. 189: 8381-6. PMID: 17827284
- D-Alanine:D-alanine ligase as a new target for the flavonoids quercetin and apigenin. | Wu, D., et al. 2008. Int J Antimicrob Agents. 32: 421-6. PMID: 18774266
- Identification of vancomycin resistance protein VanA as a D-alanine:D-alanine ligase of altered substrate specificity. | Bugg, TD., et al. 1991. Biochemistry. 30: 2017-21. PMID: 1998664
- Ellipticines and 9-acridinylamines as inhibitors of D-alanine:D-alanine ligase. | Vehar, B., et al. 2011. Bioorg Med Chem. 19: 5137-46. PMID: 21831641
- Revised mechanism of D-alanine incorporation into cell wall polymers in Gram-positive bacteria. | Reichmann, NT., et al. 2013. Microbiology (Reading). 159: 1868-1877. PMID: 23858088
- Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in Mycobacterium tuberculosis. | Prosser, GA. and de Carvalho, LP. 2013. ACS Med Chem Lett. 4: 1233-1237. PMID: 24478820
- (3-Amino-2-oxoalkyl)phosphonic acids and their analogues as novel inhibitors of D-alanine:D-alanine ligase. | Chakravarty, PK., et al. 1989. J Med Chem. 32: 1886-90. PMID: 2502630
- Catalytic Stereoinversion of L-Alanine to Deuterated D-Alanine. | Moozeh, K., et al. 2015. Angew Chem Int Ed Engl. 54: 9381-5. PMID: 26119066
- D-alanine in the frog skin peptide dermorphin is derived from L-alanine in the precursor. | Richter, K., et al. 1987. Science. 238: 200-2. PMID: 3659910
- Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. | Schmieden, V. and Betz, H. 1995. Mol Pharmacol. 48: 919-27. PMID: 7476923
- A novel antagonist, phenylbenzene omega-phosphono-alpha-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. | Saitoh, T., et al. 1994. Br J Pharmacol. 113: 165-70. PMID: 7812607
- In vivo conversion of L-serine to D-alanine in a ribosomally synthesized polypeptide. | Skaugen, M., et al. 1994. J Biol Chem. 269: 27183-5. PMID: 7961627
Activator of:
GlyR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-Alanine, 5 g | sc-203558 | 5 g | $36.00 |