Cytoplasmic CysRS Antibody (A-3): sc-390230
- Cytoplasmic CysRS Antibody (A-3) is a mouse monoclonal IgG1 κ Cytoplasmic CysRS antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 424-483 mapping near the C-terminus of Cytoplasmic CysRS of human origin
- Cytoplasmic CysRS Antibody (A-3) is recommended for detection of Cytoplasmic CysRS of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Cytoplasmic CysRS Antibody (A-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Cytoplasmic CysRS Antibody (A-3) for WB applications. This reagent is now offered in a bundle with Cytoplasmic CysRS Antibody (A-3) (see ordering information below).
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Cytoplasmic CysRS Antibody (A-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects Cytoplasmic CysRS of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Cytoplasmic CysRS antibody (A-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Cytoplasmic CysRS (A-3) antibody recognizes Cysteinyl-tRNA synthetase, a crucial enzyme in protein synthesis responsible for specific aminoacylation of tRNA with L-cysteine, essential for accurate translation of genetic information into proteins. Cytoplasmic CysRS (A-3) monoclonal antibody targets a member of the class-I aminoacyl-tRNA synthetase family consisting of 748 amino acids, functioning as a monomer that binds one zinc ion per subunit for catalytic activity. Anti-Cytoplasmic CysRS antibody (A-3) detects a protein whose chromosomal aberrations have been linked to inflammatory myofibroblastic tumors (IMTs). Cytoplasmic CysRS exists in two isoforms due to alternative splicing, highlighting complex regulation and diverse cellular roles.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Cytoplasmic CysRS Antibody (A-3) References:
- An elongation factor-associating domain is inserted into human cysteinyl-tRNA synthetase by alternative splicing. | Kim, JE., et al. 2000. Nucleic Acids Res. 28: 2866-72. PMID: 10908348
- Isolation of two cDNAs encoding functional human cytoplasmic cysteinyl-tRNA synthetase. | Davidson, E., et al. 2001. Biol Chem. 382: 399-406. PMID: 11347887
- Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor. | Cools, J., et al. 2002. Genes Chromosomes Cancer. 34: 354-62. PMID: 12112524
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. | Rush, J., et al. 2005. Nat Biotechnol. 23: 94-101. PMID: 15592455
- Acquisition of an insertion peptide for efficient aminoacylation by a halophile tRNA synthetase. | Evilia, C. and Hou, YM. 2006. Biochemistry. 45: 6835-45. PMID: 16734420
- Emergence of the universal genetic code imprinted in an RNA record. | Hohn, MJ., et al. 2006. Proc Natl Acad Sci U S A. 103: 18095-100. PMID: 17110438
- Kinetic quality control of anticodon recognition by a eukaryotic aminoacyl-tRNA synthetase. | Liu, C., et al. 2007. J Mol Biol. 367: 1063-78. PMID: 17303165
- Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea. | Fukunaga, R. and Yokoyama, S. 2007. Nat Struct Mol Biol. 14: 272-9. PMID: 17351629
- Assignment of the cysteinyl-tRNA synthetase gene (CARS) to 11p15.5. | Cruzen, ME., et al. 1993. Genomics. 15: 692-3. PMID: 8468064
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytoplasmic CysRS Antibody (A-3) | sc-390230 | 200 µg/ml | $322.00 | |||
Cytoplasmic CysRS Antibody (A-3): m-IgG Fc BP-HRP Bundle | sc-526135 | 200 µg Ab; 10 µg BP | $361.00 | |||
Cytoplasmic CysRS Antibody (A-3) AC | sc-390230 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Cytoplasmic CysRS Antibody (A-3) HRP | sc-390230 HRP | 200 µg/ml | $322.00 | |||
Cytoplasmic CysRS Antibody (A-3) FITC | sc-390230 FITC | 200 µg/ml | $336.00 | |||
Cytoplasmic CysRS Antibody (A-3) PE | sc-390230 PE | 200 µg/ml | $349.00 | |||
Cytoplasmic CysRS Antibody (A-3) Alexa Fluor® 488 | sc-390230 AF488 | 200 µg/ml | $364.00 | |||
Cytoplasmic CysRS Antibody (A-3) Alexa Fluor® 546 | sc-390230 AF546 | 200 µg/ml | $364.00 | |||
Cytoplasmic CysRS Antibody (A-3) Alexa Fluor® 594 | sc-390230 AF594 | 200 µg/ml | $364.00 | |||
Cytoplasmic CysRS Antibody (A-3) Alexa Fluor® 647 | sc-390230 AF647 | 200 µg/ml | $364.00 | |||
Cytoplasmic CysRS Antibody (A-3) Alexa Fluor® 680 | sc-390230 AF680 | 200 µg/ml | $364.00 | |||
Cytoplasmic CysRS Antibody (A-3) Alexa Fluor® 790 | sc-390230 AF790 | 200 µg/ml | $364.00 |