Cytokeratin 5/14 Antibody (LH8): sc-53259
- Cytokeratin 5/14 Antibody (LH8) is a mouse monoclonal IgM κ provided at 200 µg/ml
- raised against foreskin keratinocytes of human origin
- recommended for detection of Cytokeratin 5/14 of human origin by IF
- See Cytokeratin 14 (LL001): sc-53253 for Cytokeratin 5/14 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Cytokeratin 5/14 Antibody (LH8). This work is in progress.
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SEE ALSO...
Cytokeratin 5/14 Antibody (LH8) is a mouse monoclonal IgM antibody that detects Cytokeratin 5/14 in human samples through immunofluorescence (IF) applications. Cytokeratin 5 and Cytokeratin 14 are crucial components of the cytoskeletal structure in epithelial cells, primarily found in the basal layer of stratified squamous epithelia, such as the skin and the lining of the esophagus. Anti-Cytokeratin 5/14 antibody (LH8) helps identify these proteins that maintain structural integrity and mechanical resilience of tissues, particularly in response to physical stress and injury. Cytokeratin 5 and Cytokeratin 14 interact with other cytokeratins and proteins, such as desmoplakin, playing a significant role in forming desmosomes, which are essential for cell-cell adhesion. This interaction supports the overall architecture of epithelial tissues and contributes to signaling pathways that regulate cell proliferation and differentiation. Cytokeratin 5/14 (LH8) monoclonal antibody serves as a valuable marker in diagnosing various epithelial tumors, making anti-Cytokeratin 5/14 antibody (LH8) an invaluable tool for researchers and clinicians in understanding epithelial biology and pathology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytokeratin 5/14 Antibody (LH8) | sc-53259 | 200 µg/ml | $316.00 |