Cytokeratin 19 Antibody (RCK108): sc-53003

Cytokeratin 19 Antibody (RCK108) is a mouse monoclonal IgG1 antibody that detects Cytokeratin 19 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Anti-Cytokeratin 19 antibody (RCK108) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Cytokeratin 19 is a vital component of the cytoskeletal structure in epithelial cells, playing a crucial role in maintaining cellular integrity and providing mechanical support. Expression of Cytokeratin 19 is particularly significant in epithelial differentiation and tissue specialization, making Cytokeratin 19 an important marker for various pathological conditions. Cytokeratin 19 is associated with several types of cancer, including lung cancer and hepatoma, where Cytokeratin 19 fragments can serve as valuable biomarkers for diagnosis and prognosis. CYFRA 21-1, a Cytokeratin 19 fragment found in serum, has been identified as a promising tumor marker, highlighting Cytokeratin 19′s relevance in clinical oncology. Cytokeratin 19 (RCK108) monoclonal antibody enables researchers to effectively study Cytokeratin 19 expression and function in both normal and diseased tissues, contributing to a better understanding of epithelial cell biology and cancer pathology.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Cytokeratin 19 Antibody (RCK108) has 9 citations in a variety of scientific publications.

Primary antibodies like Anti-Cytokeratin 19 Antibody (RCK108) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Cytokeratin 19 Antibody (RCK108) Specifications

Alternate Product Name: KRT19

Product Clone Name: RCK108

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Cytokeratin 19

Epitope Species: human

Product Reactivity/Detection: Cytokeratin 19

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), FCM

Vialing Information: Each vial contains 200 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 9 citations in various scientific publications

Available Conjugates/Forms for Cytokeratin 19 Antibody (RCK108): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Cytokeratin 19 antibody is Cytokeratin 19 Antibody (A-3): sc-376126.